The treatment of individual patients in cardiology practice increasingly relies on advanced
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …

For both the atria and ventricles, fibrosis is generally recognized as one of the key
determinants of conduction disturbances. By definition, fibrosis refers to an increased …

Abstract Background and Objective: Cardiac electrophysiology is a medical specialty with a
long and rich tradition of computational modeling. Nevertheless, no community standard for …

Atrial fibrillation (AF)—the most common arrhythmia—significantly increases the risk of
stroke and heart failure. Although catheter ablation can restore normal heart rhythms …

Background: Current ablation therapy for atrial fibrillation is suboptimal, and long-term
response is challenging to predict. Clinical trials identify bedside properties that provide only …

In the chronic stage of myocardial infarction, a significant number of patients develop life-
threatening ventricular tachycardias (VT) due to the arrhythmogenic nature of the remodeled …

Background—Recent studies have demonstrated conflicting mechanisms underlying atrial
fibrillation (AF), with the spatial resolution of data often cited as a potential reason for the …

AF is a heterogeneous rhythm disorder that is related to a wide spectrum of etiologies and
has broad clinical presentations. Mechanisms underlying AF are complex and remain …

Integrating spatial information about atrial physiology and anatomy in a single patient from
multimodal datasets, as well as generalizing these data across patients, requires a common …

Atrial anisotropy affects electrical propagation patterns, anchor locations of atrial reentrant
drivers, and atrial mechanics. However, patient-specific atrial fibre fields and anisotropy …