Cerebral small vessel disease: from a focal to a global perspective

A Ter Telgte, EMC Van Leijsen, K Wiegertjes… - Nature Reviews …, 2018 - nature.com
Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among
elderly individuals and is recognized as a major vascular contributor to dementia, cognitive …

Impact of hypertension on cognitive function: a scientific statement from the American Heart Association

C Iadecola, K Yaffe, J Biller, LC Bratzke, FM Faraci… - …, 2016 - Am Heart Assoc
Background—Age-related dementia, most commonly caused by Alzheimer disease or
cerebrovascular factors (vascular dementia), is a major public health threat. Chronic arterial …

Vascular cognitive impairment

M Dichgans, D Leys - Circulation research, 2017 - Am Heart Assoc
Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both.
Vascular cognitive impairment refers to all forms of cognitive disorder associated with …

Associations between vascular risk factors and brain MRI indices in UK Biobank

SR Cox, DM Lyall, SJ Ritchie, ME Bastin… - European heart …, 2019 - academic.oup.com
Aims Several factors are known to increase risk for cerebrovascular disease and dementia,
but there is limited evidence on associations between multiple vascular risk factors (VRFs) …

White matter hyperintensities and imaging patterns of brain ageing in the general population

M Habes, G Erus, JB Toledo, T Zhang, N Bryan… - Brain, 2016 - academic.oup.com
White matter hyperintensities are associated with increased risk of dementia and cognitive
decline. The current study investigates the relationship between white matter …

White matter injury in ischemic stroke

Y Wang, G Liu, D Hong, F Chen, X Ji, G Cao - Progress in neurobiology, 2016 - Elsevier
Stroke is one of the major causes of disability and mortality worldwide. It is well known that
ischemic stroke can cause gray matter injury. However, stroke also elicits profound white …

Association between midlife obesity and its metabolic consequences, cerebrovascular disease, and cognitive decline

F Morys, M Dadar, A Dagher - The Journal of Clinical …, 2021 - academic.oup.com
Context Chronic obesity is associated with several complications, including cognitive
impairment and dementia. However, we have only piecemeal knowledge of the mechanisms …

Cerebral small vessel disease: Pathological mechanisms and potential therapeutic targets

Y Gao, D Li, J Lin, AM Thomas, J Miao… - Frontiers in aging …, 2022 - frontiersin.org
Cerebral small vessel disease (CSVD) represents a diverse cluster of cerebrovascular
diseases primarily affecting small arteries, capillaries, arterioles and venules. The diagnosis …

Post-stroke epilepsy

T Tanaka, M Ihara - Neurochemistry international, 2017 - Elsevier
Post-stroke epilepsy (PSE) is a common complication after stroke, yet treatment options
remain limited. While many physicians prescribe antiepileptic drugs (AED) for secondary …

Cerebral small vessel disease: neuroimaging markers and clinical implication

X Chen, J Wang, Y Shan, W Cai, S Liu, M Hu, S Liao… - Journal of …, 2019 - Springer
Cerebral small vessel disease (CSVD) is a broad category of cerebrovascular diseases
which primarily affect the perforating arterioles, capillaries and venules with multiple distinct …