While conventional radiography and MRI have a well-established role in the assessment of
patients with knee osteoarthritis, ultrasound is considered a complementary and additional …

Musculoskeletal (MSK) ultrasound has well-established advantages, able to investigate very
small structures with high resolution and a quick and real-time dynamic evaluation with the …

The objective of this study was to develop an in vitro cartilage degradation model that
emulates the damage seen in early-stage osteoarthritis. To this end, cartilage explants were …

Matrix metalloproteinases (MMPs) play a crucial role in enzymatically digesting cartilage
extracellular matrix (ECM) components, resulting in degraded cartilage with altered …

OBJECTIVE: Mechanical indentation and ultrasound (US) indentation instruments have
been introduced for quantitative assessment of cartilage properties in vivo. In this study, we …

Previous studies have suggested that quantitative ultrasound imaging could sensitively
diagnose degeneration of the articular surface and changes in the subchondral bone during …

Osteoarthritis (OA) is a prevalent cause of joint algesia, loss of function, and disability in
adults, with cartilage injury being its core pathological manifestation. Since cartilage …

In osteoarthrosis, pathological features of articular cartilage are associated with
degeneration and nanomechanical changes. The aim of this paper is to show that …

Advances in current clinical modalities, including magnetic resonance imaging and
computed tomography, allow for earlier diagnoses of cartilage damage that could mitigate …

Osteoarthritis (OA) is one of the most common joint diseases among adults, and its early
detection is still not possible. In this study, high-frequency ultrasound and ultrasound …