[HTML][HTML] Modulation of L-type calcium channels in Alzheimer's disease: A potential therapeutic target
CA Crossley, V Rajani, Q Yuan - Computational and Structural …, 2023 - Elsevier
Calcium plays a fundamental role in various signaling pathways and cellular processes in
the human organism. In the nervous system, voltage-gated calcium channels such as L-type …
the human organism. In the nervous system, voltage-gated calcium channels such as L-type …
Amyloid Beta Peptide-Mediated Alterations in Mitochondrial Dynamics and its Implications for Alzheimer's Disease
LÁ Monsalvo-Maraver, M Maya-López… - CNS & Neurological …, 2023 - ingentaconnect.com
Alzheimer's disease (AD) is considered the most frequent neurodegenerative disorder
worldwide, compromising cognitive function in patients, with an average incidence of 1-3 …
worldwide, compromising cognitive function in patients, with an average incidence of 1-3 …
Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration
KC Ryan, Z Ashkavand, S Sarasija, JT Laboy… - Aging …, 2021 - Wiley Online Library
Metabolic dysfunction and protein aggregation are common characteristics that occur in age‐
related neurodegenerative disease. However, the mechanisms underlying these …
related neurodegenerative disease. However, the mechanisms underlying these …