Solid-state NMR spectroscopy is one of the most commonly used techniques to study the
atomic-resolution structure and dynamics of various chemical, biological, material, and …

In recent years many efforts have been devoted to the screening and the study of new solid-
state forms of old active pharmaceutical ingredients (APIs) with salification or co …

Interest in molecular crystals has grown thanks to their relevance to pharmaceuticals,
organic semiconductor materials, foods, and many other applications. Electronic structure …

Developments of NMR methodology to characterise the structures of molecular organic
structures are reviewed, concentrating on the previous decade of research in which density …

The main goal of a novel drug development is to obtain it with optimal physiochemical,
pharmaceutical and biological properties. Pharmaceutical companies and scientists modify …

Dynamic nuclear polarization (DNP) solid-state NMR has been applied to powdered
microcrystalline solids to obtain sensitivity enhancements on the order of 100. Glucose …

In spite of tremendous progress made in pulse sequence designs and sophisticated
hardware developments, methods to improve sensitivity and resolution in solid-state NMR …

Dynamic nuclear polarization (DNP) enhanced solid-state NMR spectroscopy at 9.4 T is
demonstrated for the detailed atomic-level characterization of commercial pharmaceutical …

The performance of fragment-based ab initio1H, 13C, 15N and 17O chemical shift
predictions is assessed against experimental NMR chemical shift data in four benchmark …

Amorphous solid dispersions (ASDs) are one of the frontier strategies to improve solubility
and dissolution rate of poorly soluble drugs and hence tackling the growing challenges in …