Because of the association between aberrant nuclear structure and tumour grade, nuclear
morphology is an indispensible criterion in the current pathological assessment of cancer …

Kinesin-2 was first purified as a heterotrimeric, anterograde, microtubule-based motor
consisting of two distinct kinesin-related subunits and a novel associated protein (KAP) that …

Abstract Adenomatous Polyposis Coli (APC) protein is mostly known as a tumor suppressor
that regulates Wnt signaling, but is also an important cytoskeletal protein. Mutations in the …

Nucleocytoplasmic transport is an essential cellular activity and occurs via nuclear pore
complexes (NPCs) that reside in the double membrane of the nuclear envelope. Significant …

The interplay of infection and genetics in acute necrotizing... : Current Opinion in Pediatrics
The interplay of infection and genetics in acute necrotizing encephalopathy : Current Opinion …

Since its discovery as the major tumour suppressor in colorectal cancer, the adenomatous
polyposis coli (APC) protein has emerged as a multi-functional protein that directly or …

The formation of the nuclear envelope and the subsequent compartmentalization of the
genome is a defining feature of eukaryotes. Traditionally, the nuclear envelope was purely …

In higher eukaryotes, most mRNAs that encode secreted or membrane-bound proteins
contain elements that promote an alternative mRNA nuclear export (ALREX) pathway. Here …

Dominant missense mutations in RanBP2/Nup358 cause Acute Necrotizing Encephalopathy
(ANE), a pediatric disease where seemingly healthy individuals develop a cytokine storm …

Micro RNA (mi RNA)‐guided mRNA repression, mediated by the mi RNA‐induced silencing
complex (mi RISC), is an important component of post‐transcriptional gene silencing …