DNA vaccination has suddenly become a favoured strategy for inducing immunity. The
molecular precision offered by gene-based vaccines, together with the facility to include …

Background: Plasmid DNA vaccination combined with electroporation (EP) provides a
promising approach for the prevention of infectious diseases and for cancer immunotherapy …

Genetic technology allows construction of DNA vaccines encoding selected tumor antigens
together with molecules to direct and amplify the desired effector pathways. Their enormous …

Background The highly attenuated vaccinia virus strain NYVAC expressing HIV-1
components has been evaluated as a vaccine candidate in preclinical and clinical trials with …

ABSTRACT DNA vaccines offer advantage over conventional vaccines, as they are safer to
use, easier to produce, and able to induce humoral as well cellular immune responses …

Background DNA vaccines have been shown to be an effective approach to induce antigen‐
specific cellular and humoral immunity. However, the lower immune intensity in clinical trials …

The Wilms tumor antigen, WT1, is associated with several human cancers, including
leukemia. We evaluated WT1 as an immunotherapeutic target using our proven DNA fusion …

Introduction: Cancer vaccines represent one of the oldest immunotherapy strategies. A
variety of tumor-associated antigens have been exploited to investigate their …

The employment of the immune system to treat malignant disease represents an active area
of biomedical research. The specificity of the immune response and potential for …

Vaccination is historically one of the most important methods for preventing infectious
diseases in humans and animals. Due to recent advances in understanding the biology of …