Merkel cell carcinoma (MCC) is a rare skin cancer, accounting for less than 1% of all
cutaneous malignancies. It is found predominantly in white populations and risk factors …

Merkel cell carcinoma (MCC) is a rare but highly aggressive skin cancer with
neuroendocrine features. MCC pathogenesis is associated with either the presence of …

Merkel cell carcinoma (MCC) is an uncommon primary cutaneous neuroendocrine cancer. It
most commonly presents as an indurated plaque or nodule on sun-damaged skin in elderly …

Purpose: Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous malignancy, which
has demonstrated sensitivity to immune checkpoint inhibitor therapy. Here, we perform the …

Merkel cell carcinoma (MCC) is an aggressive neuroendocrine carcinoma of the skin with
two distinct etiologies. Clonal integration of Merkel cell polyomavirus DNA into the tumor …

Merkel cell carcinoma (MCC) is a rare but lethal cancer with the highest case-by-case fatality
rate among all skin cancers. Eighty percent of cancers are associated with the Merkel cell …

Background Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine carcinoma
of the skin caused by either the integration of Merkel cell polyomavirus (MCPyV) and …

Simple Summary Merkel cell polyomavirus (MCPyV) is a widespread virus that is present on
human skin. Infection occurs early in life, and up to 90% of adults have antibodies against …

Highlights•Viral infections cause approximately 12% of all human cancers.•Viral cancers
represent rare outcomes of frequent infections.•Oncogenicity of viral proteins reflects their …

High-grade neuroendocrine neoplasms (HG-NENs) are clinically aggressive diseases, the
classification of which has recently been redefined. They now include both poorly …