[HTML][HTML] Amyloid β-based therapy for Alzheimer's disease: Challenges, successes and future
Y Zhang, H Chen, R Li, K Sterling… - Signal transduction and …, 2023 - nature.com
Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer's disease
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …
[HTML][HTML] Alzheimer's disease prevention: from risk factors to early intervention
M Crous-Bou, C Minguillón, N Gramunt… - Alzheimer's research & …, 2017 - Springer
Due to the progressive aging of the population, Alzheimer's disease (AD) is becoming a
healthcare burden of epidemic proportions for which there is currently no cure …
healthcare burden of epidemic proportions for which there is currently no cure …
Defeating Alzheimer's disease and other dementias: a priority for European science and society
Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …
Potential for primary prevention of Alzheimer's disease: an analysis of population-based data
Background Recent estimates suggesting that over half of Alzheimer's disease burden
worldwide might be attributed to potentially modifiable risk factors do not take into account …
worldwide might be attributed to potentially modifiable risk factors do not take into account …
[HTML][HTML] Mediterranean diet, cognitive function, and dementia: a systematic review of the evidence
SD Petersson, E Philippou - Advances in Nutrition, 2016 - Elsevier
A growing body of evidence suggests that adherence to the Mediterranean diet (MD) may
protect against cognitive decline and dementia. Many epidemiologic studies and several …
protect against cognitive decline and dementia. Many epidemiologic studies and several …
Hearing loss and cognitive decline in older adults
Background Whether hearing loss is independently associated with accelerated cognitive
decline in older adults is unknown. Methods We studied 1984 older adults (mean age, 77.4 …
decline in older adults is unknown. Methods We studied 1984 older adults (mean age, 77.4 …
[HTML][HTML] Hearing loss and cognition: the role of hearing AIDS, social isolation and depression
Hearing loss is associated with poor cognitive performance and incident dementia and may
contribute to cognitive decline. Treating hearing loss with hearing aids may ameliorate …
contribute to cognitive decline. Treating hearing loss with hearing aids may ameliorate …
[HTML][HTML] Aerobic exercise for Alzheimer's disease: A randomized controlled pilot trial
JK Morris, ED Vidoni, DK Johnson, A Van Sciver… - PloS one, 2017 - journals.plos.org
Background There is increasing interest in the role of physical exercise as a therapeutic
strategy for individuals with Alzheimer's disease (AD). We assessed the effect of 26 weeks (6 …
strategy for individuals with Alzheimer's disease (AD). We assessed the effect of 26 weeks (6 …
[HTML][HTML] Alzheimer mechanisms and therapeutic strategies
There are still no effective treatments to prevent, halt, or reverse Alzheimer's disease, but
research advances over the past three decades could change this gloomy picture. Genetic …
research advances over the past three decades could change this gloomy picture. Genetic …
The projected effect of risk factor reduction on Alzheimer's disease prevalence
Summary At present, about 33· 9 million people worldwide have Alzheimer's disease (AD),
and prevalence is expected to triple over the next 40 years. The aim of this Review was to …
and prevalence is expected to triple over the next 40 years. The aim of this Review was to …