Methamphetamine use: a comprehensive review of molecular, preclinical and clinical findings

WJ Panenka, RM Procyshyn, T Lecomte… - Drug and alcohol …, 2013 - Elsevier
Methamphetamine (MA) is a highly addictive psychostimulant drug that principally affects the
monoamine neurotransmitter systems of the brain and results in feelings of alertness …

Drug addiction: the neurobiology of disrupted self-control

RD Baler, ND Volkow - Trends in molecular medicine, 2006 - cell.com
The nature of addiction is often debated along moral versus biological lines. However,
recent advances in neuroscience offer insights that might help bridge the gap between these …

Dopamine in drug abuse and addiction: results of imaging studies and treatment implications

ND Volkow, JS Fowler, GJ Wang… - Archives of …, 2007 - jamanetwork.com
Imaging studies have provided new insights on the role of dopamine (DA) in drug abuse and
addiction in the human brain. These studies have shown that the reinforcing effects of drugs …

The need for speed: an update on methamphetamine addiction

AM Barr, WJ Panenka, GW MacEwan… - Journal of psychiatry and …, 2006 - jpn.ca
The psychostimulant methamphetamine (MA) is a highly addictive drug that has surged in
popularity over the last decade in North America. A burgeoning number of clandestine drug …

Covalent modifiers: an orthogonal approach to drug design

MH Potashman, ME Duggan - Journal of medicinal chemistry, 2009 - ACS Publications
In an effort to discover small molecule drug candidates with attractive toxicity profiles, the
pharmaceutical industry has predominantly sought compounds that modulate target proteins …

Antiepileptic drugs in non-epilepsy disorders: relations between mechanisms of action and clinical efficacy

CJ Landmark - CNS drugs, 2008 - Springer
Antiepileptic drugs (AEDs) are used extensively to treat multiple non-epilepsy disorders,
both in neurology and psychiatry. This article provides a review of the clinical efficacy of …

Implications of chronic methamphetamine use: a literature review

CW Meredith, C Jaffe, K Ang-Lee… - Harvard review of …, 2005 - Taylor & Francis
Methamphetamine (MA) abuse is increasing to epidemic proportions, both nationally and
globally. Chronic MA use has been linked to significant impairments in different arenas of …

Pharmacological approaches to methamphetamine dependence: a focused review

L Karila, A Weinstein, HJ Aubin… - British journal of …, 2010 - Wiley Online Library
Methamphetamine dependence is a serious worldwide public health problem with major
medical, psychiatric, socioeconomic and legal consequences. Various neuronal …

[HTML][HTML] Imaging the addicted human brain

JS Fowler, ND Volkow, CA Kassed… - Science & practice …, 2007 - ncbi.nlm.nih.gov
Modern imaging techniques enable researchers to observe drug actions and consequences
as they occur and persist in the brains of abusing and addicted individuals. This article …

The methamphetamine epidemic: implications for HIV prevention and treatment

G Colfax, S Shoptaw - Current Hiv/aids Reports, 2005 - Springer
Methamphetamine and related amphetamine compounds are among the most commonly
used illicit drugs, with over 35 million users worldwide. In the United States, admissions for …