Accumulation and turnover of extracellular matrix is a hallmark of tissue injury, repair and
remodeling in human diseases. Hyaluronan is a major component of the extracellular matrix …

Idiopathic pulmonary fibrosis (IPF) is a debilitating and fatal condition that causes severe
scarring of the lungs. While the pathogenesis of IPF continues to be extensively studied and …

Hyaluronidases are enzymes that mainly degrade hyaluronan, the major glycosaminoglycan
of the interstitial matrix. They are involved in several pathological and physiological activities …

Delivering drugs through inhalation for systemic and local applications has been in practice
since several decades to treat various diseases. In recent times, inhalation drug delivery is …

The present study was initiated to understand the effect of PLGA concentration, PVA
concentration, internal‐external phase ratio, homogenization speed, and homogenization …

PEGylation was firstly described around 50 years ago and has been used for more than 30
years as a strategy to improve the drugability of biopharmaceuticals. However, it remains …

Background Naja annulifera is a medically important venomous snake occurring in some of
the countries in Sub-Saharan Africa. Accidental bites result in severe coagulation …

Objective and design Investigate survival outcomes, and immunological and metabolomic
effects of hyaluronidase (Hz) treatment during mouse models of acute inflammation and …

We developed a facile fabrication method for preparing poly (ethylene glycol)(PEG)-coated
poly (lactic-co-glycolic acid)(PLGA) microspheres with homogeneous size distribution via a …

Background. Idiopathic pulmonary fibrosis (IPF), the most common interstitial lung disease,
arises from transforming growth factor beta 1‐(TGFβ1‐) induced aberrant fibroproliferation in …