A brief history of bird flu
In 1918, a strain of influenza A virus caused a human pandemic resulting in the deaths of 50
million people. A century later, with the advent of sequencing technology and corresponding …
million people. A century later, with the advent of sequencing technology and corresponding …
Reverse zoonosis of influenza to swine: new perspectives on the human–animal interface
MI Nelson, AL Vincent - Trends in microbiology, 2015 - cell.com
The origins of the 2009 influenza A (H1N1) pandemic in swine are unknown, highlighting
gaps in our understanding of influenza A virus (IAV) ecology and evolution. We review how …
gaps in our understanding of influenza A virus (IAV) ecology and evolution. We review how …
Topology of viral evolution
JM Chan, G Carlsson… - Proceedings of the …, 2013 - National Acad Sciences
The tree structure is currently the accepted paradigm to represent evolutionary relationships
between organisms, species or other taxa. However, horizontal, or reticulate, genomic …
between organisms, species or other taxa. However, horizontal, or reticulate, genomic …
Deep sequencing: becoming a critical tool in clinical virology
ME Quiñones-Mateu, S Avila, G Reyes-Teran… - Journal of clinical …, 2014 - Elsevier
Population (Sanger) sequencing has been the standard method in basic and clinical DNA
sequencing for almost 40 years; however, next-generation (deep) sequencing …
sequencing for almost 40 years; however, next-generation (deep) sequencing …
Current and prospective control strategies of influenza A virus in swine
HA Salvesen, CBA Whitelaw - Porcine health management, 2021 - Springer
Abstract Background Influenza A Viruses (IAV) are endemic pathogens of significant
concern in humans and multiple keystone livestock species. Widespread morbidity in swine …
concern in humans and multiple keystone livestock species. Widespread morbidity in swine …
RNA virus reassortment: an evolutionary mechanism for host jumps and immune evasion
Reassortment is an evolutionary mechanism of segmented RNA viruses that plays an
important but ill-defined role in virus emergence and interspecies transmission. Recent …
important but ill-defined role in virus emergence and interspecies transmission. Recent …
Determinants of virulence of influenza A virus
EJA Schrauwen, M de Graaf, S Herfst… - European journal of …, 2014 - Springer
Influenza A viruses cause yearly seasonal epidemics and occasional global pandemics in
humans. In the last century, four human influenza A virus pandemics have occurred …
humans. In the last century, four human influenza A virus pandemics have occurred …
Reassortment between influenza B lineages and the emergence of a coadapted PB1–PB2–HA gene complex
Influenza B viruses make a considerable contribution to morbidity attributed to seasonal
influenza. Currently circulating influenza B isolates are known to belong to two antigenically …
influenza. Currently circulating influenza B isolates are known to belong to two antigenically …
Reassortment patterns of avian influenza virus internal segments among different subtypes
Background The segmented RNA genome of avian Influenza viruses (AIV) allows genetic
reassortment between co-infecting viruses, providing an evolutionary pathway to generate …
reassortment between co-infecting viruses, providing an evolutionary pathway to generate …
Origins of the 1918 pandemic: revisiting the swine “mixing vessel” hypothesis
How influenza A viruses host-jump from animal reservoir species to humans, which can
initiate global pandemics, is a central question in pathogen evolution. The zoonotic and …
initiate global pandemics, is a central question in pathogen evolution. The zoonotic and …