Polyphenols in cancer prevention: New insights

G Briguglio, C Costa, M Pollicino… - International …, 2020 - spandidos-publications.com
A huge volume of literature data suggests that a diet rich in fruits and vegetables, mostly due
to the contribution of natural polyphenols, could reduce the incidence of specific cancers …

Inflammation, not cholesterol, is a cause of chronic disease

A Tsoupras, R Lordan, I Zabetakis - Nutrients, 2018 - mdpi.com
Since the Seven Countries Study, dietary cholesterol and the levels of serum cholesterol in
relation to the development of chronic diseases have been somewhat demonised. However …

Generation and multiomic profiling of a TP53/CDKN2A double-knockout gastroesophageal junction organoid model

H Zhao, Y Cheng, A Kalra, K Ma, Y Zheng… - Science translational …, 2022 - science.org
Inactivation of the tumor suppressor genes tumor protein p53 (TP53) and cyclin-dependent
kinase inhibitor 2A (CDKN2A) occurs early during gastroesophageal junction (GEJ) …

Phospholipids of animal and marine origin: Structure, function, and anti-inflammatory properties

R Lordan, A Tsoupras, I Zabetakis - Molecules, 2017 - mdpi.com
In this review paper, the latest literature on the functional properties of phospholipids in
relation to inflammation and inflammation-related disorders has been critically appraised …

Arterial hypertension and interleukins: potential therapeutic target or future diagnostic marker?

DM Tanase, EM Gosav, S Radu… - International journal …, 2019 - Wiley Online Library
Hypertension as a multifactorial pathology is one of the most important cardiovascular risk
factors, affecting up to 30‐40% of the general population. Complex immune responses are …

Forty years since the structural elucidation of platelet-activating factor (PAF): historical, current, and future research perspectives

R Lordan, A Tsoupras, I Zabetakis, CA Demopoulos - Molecules, 2019 - mdpi.com
In the late 1960s, Barbaro and Zvaifler described a substance that caused antigen induced
histamine release from rabbit platelets producing antibodies in passive cutaneous …

Macroalgal proteins: a review

RO Brien, M Hayes, G Sheldrake, B Tiwari, P Walsh - Foods, 2022 - mdpi.com
Population growth is the driving change in the search for new, alternative sources of protein.
Macroalgae (otherwise known as seaweeds) do not compete with other food sources for …

[HTML][HTML] Tumor macroenvironment and metabolism

W Al-Zhoughbi, J Huang, GS Paramasivan, H Till… - Seminars in …, 2014 - Elsevier
In this review we introduce the concept of the tumor macroenvironment and explore it in the
context of metabolism. Tumor cells interact with the tumor microenvironment including …

The platelet–cancer loop

HA Goubran, T Burnouf, M Radosevic… - European journal of …, 2013 - Elsevier
The relationship between cancer and thrombosis has been established since 1865 when
Armand Trousseau described superficial thrombophlebitis as forewarning sign of occult …

Metal complexes as potential modulators of inflammatory and autoimmune responses

CH Leung, S Lin, HJ Zhong, DL Ma - Chemical Science, 2015 - pubs.rsc.org
Over the past few decades, the realm of inorganic medicinal chemistry has been dominated
by the study of the anti-cancer properties of transition metal complexes, particularly those …