In the past decade, the field of organic synthesis has witnessed tremendous advancements
in the areas of photoredox catalysis, electrochemistry, C–H activation, reductive coupling …

Continuous stirred tank reactors (CSTRs) facilitate chemical manufacture in continuous flow
and have been used for decades. They excel at solid handling and have well understood …

The pharmaceutical industry has witnessed exponential growth in transforming operations
towards continuous manufacturing to increase profitability, reduce waste and extend product …

This manuscript provides the results of an in-depth survey assessment of the capabilities,
experience, and perspectives on continuous processing in the pharmaceutical sector, with …

Privileged scaffolds as starting points toward biologically active molecules represent a
neuralgic point in drug discovery. The ability of synthetic chemists concerned with their …

Pharmaceutical production remains one of the last industries that predominantly uses batch
processes, which are inefficient and can cause drug shortages due to the long lead times or …

We report the use of continuous flow processing to enable the first two steps of a new route
toward a cannabinoid receptor type 2 agonist, RG7774. First, an alkyl azide is formed using …

Recent cyberattacks against industrial control systems highlight the criticality of preventing
future attacks from disrupting plants economically or, more critically, from impacting plant …

Microflow chemistry is one of the newest and most efficient technologies used today for the
safe and effective production of medicines. In this paper, we show the use of this technology …

This article outlines the development of a continuous flow process for the manufacture of a
key intermediate of the active pharmaceutical ingredient ipatasertib for the treatment of …