[HTML][HTML] Pregnancy-associated changes in pharmacokinetics: a systematic review
G Pariente, T Leibson, A Carls, T Adams-Webber… - PLoS …, 2016 - journals.plos.org
Background Women are commonly prescribed a variety of medications during pregnancy.
As most organ systems are affected by the substantial anatomical and physiological …
As most organ systems are affected by the substantial anatomical and physiological …
HIV-1 integrase inhibitors: a comparative review of efficacy and safety
KK Scarsi, JP Havens, AT Podany, SN Avedissian… - Drugs, 2020 - Springer
The newest class of antiretrovirals for all persons living with HIV are the integrase strand
transfer inhibitors (INSTIs). Since 2007, five INSTIs have been introduced: raltegravir …
transfer inhibitors (INSTIs). Since 2007, five INSTIs have been introduced: raltegravir …
[HTML][HTML] Integrase strand transfer inhibitors are effective anti-HIV drugs
Integrase strand transfer inhibitors (INSTIs) are currently recommended for the first line
treatment of human immunodeficiency virus type one (HIV-1) infection. The first-generation …
treatment of human immunodeficiency virus type one (HIV-1) infection. The first-generation …
Dolutegravir pharmacokinetics in pregnant and postpartum women living with HIV
Objective: To evaluate dolutegravir pharmacokinetics during pregnancy compared with
postpartum and in infant washout samples after delivery. Design: Ongoing, nonrandomized …
postpartum and in infant washout samples after delivery. Design: Ongoing, nonrandomized …
Comparative clinical pharmacokinetics and pharmacodynamics of HIV-1 integrase strand transfer inhibitors
AT Podany, KK Scarsi, CV Fletcher - Clinical pharmacokinetics, 2017 - Springer
Abstract Dolutegravir (DTG), elvitegravir (EVG) and raltegravir (RAL) are members of the
latest class of antiretrovirals (ARVs) that have become available to treat human …
latest class of antiretrovirals (ARVs) that have become available to treat human …
HIV viraemia and mother‐to‐child transmission risk after antiretroviral therapy initiation in pregnancy in Cape Town, South Africa
Objectives Maternal HIV viral load (VL) drives mother‐to‐child HIV transmission (MTCT) risk
but there are few data from sub‐Saharan Africa, where most MTCT occurs. We investigated …
but there are few data from sub‐Saharan Africa, where most MTCT occurs. We investigated …
Evaluating cabotegravir/rilpivirine long-acting, injectable in the treatment of HIV infection: emerging data and therapeutic potential
C Fernandez, CL van Halsema - HIV/AIDS-Research and Palliative …, 2019 - Taylor & Francis
Cabotegravir and rilpivirine long-acting injectable antiretroviral therapy for the treatment of
HIV-1 infection brings promise of a new mode of delivery and potential solutions to some …
HIV-1 infection brings promise of a new mode of delivery and potential solutions to some …
[HTML][HTML] HIV in pregnancy: Mother-to-child transmission, pharmacotherapy, and toxicity
An estimated 1.3 million pregnant women were living with HIV in 2018. HIV infection is
associated with adverse pregnancy outcomes and all HIV-positive pregnant women …
associated with adverse pregnancy outcomes and all HIV-positive pregnant women …
Comparative clinical pharmacokinetics and pharmacodynamics of HIV-1 integrase strand transfer inhibitors: an updated review
Abstract Bictegravir, cabotegravir, dolutegravir, elvitegravir, and raltegravir are members of
the latest class of antiretrovirals available to treat human immunodeficiency virus (HIV) …
the latest class of antiretrovirals available to treat human immunodeficiency virus (HIV) …
[HTML][HTML] Pharmacokinetics of HIV-integrase inhibitors during pregnancy: mechanisms, clinical implications and knowledge gaps
R van der Galiën, R Ter Heine, R Greupink… - Clinical …, 2019 - Springer
Prevention of mother-to-child transmission of HIV and optimal maternal treatment are the
most important goals of antiretroviral therapy in pregnant women with HIV. These goals may …
most important goals of antiretroviral therapy in pregnant women with HIV. These goals may …