Biological evaluation and molecular docking studies of novel 1, 3, 4-oxadiazole derivatives of 4, 6-dimethyl-2-sulfanylpyridine-3-carboxamide
To date, chronic inflammation is involved in most main human pathologies such as cancer,
and autoimmune, cardiovascular or neurodegenerative disorders. Studies suggest that …
and autoimmune, cardiovascular or neurodegenerative disorders. Studies suggest that …
In-Silico Design, Synthesis, and Pharmacological Evaluation of Oxadiazole-Based Selective Cyclo-oxygenase-2 Inhibitors
A series of oxadiazole-based five-membered heterocyclic derivatives was designed and
synthesized with the intent of exclusive cyclo-oxygenase-2 (COX-2) inhibition to acquire anti …
synthesized with the intent of exclusive cyclo-oxygenase-2 (COX-2) inhibition to acquire anti …
Synthesis, Characterization and Antimicrobial Evaluation for New Esters Derivatives Containing Two 1, 3, 4-Oxadiazole Units
IAAH Hamdan, JH Tomma - Iraqi Journal of Science, 2024 - ijs.uobaghdad.edu.iq
This work includes the synthesis of new ester compounds containing two 1, 3, 4-oxadiazole
rings, 15a-c and 16a-c. This was done over seven steps, starting with p-acetamido-phenol 1 …
rings, 15a-c and 16a-c. This was done over seven steps, starting with p-acetamido-phenol 1 …