Implications of subclinical tuberculosis for vaccine trial design and global effect
GJ Churchyard, RMGJ Houben, K Fielding… - The Lancet …, 2024 - thelancet.com
Tuberculosis is a leading cause of death from an infectious agent globally. Infectious
subclinical tuberculosis accounts for almost half of all tuberculosis cases in national …
subclinical tuberculosis accounts for almost half of all tuberculosis cases in national …
Diagnostic accuracy of computer-aided detection during active case finding for pulmonary tuberculosis in Africa: a systematic review and meta-analysis
AJ Scott, T Perumal, A Hohlfeld… - Open forum …, 2024 - academic.oup.com
Background Computer-aided detection (CAD) may be a useful screening tool for
tuberculosis (TB). However, there are limited data about its utility in active case finding (ACF) …
tuberculosis (TB). However, there are limited data about its utility in active case finding (ACF) …
[HTML][HTML] Integrated plasma proteomics identifies tuberculosis-specific diagnostic biomarkers
HF Schiff, NF Walker, C Ugarte-Gil, M Tebruegge… - JCI insight, 2024 - ncbi.nlm.nih.gov
BACKGROUND Novel biomarkers to identify infectious patients transmitting Mycobacterium
tuberculosis are urgently needed to control the global tuberculosis (TB) pandemic. We …
tuberculosis are urgently needed to control the global tuberculosis (TB) pandemic. We …
Subclinical tuberculosis: a meta-analysis of prevalence and scoping review of definitions, prevalence and clinical characteristics
Background: This scoping review aimed to characterise definitions used to describe
subclinical tuberculosis (TB), estimate the prevalence in different populations and describe …
subclinical tuberculosis (TB), estimate the prevalence in different populations and describe …
[HTML][HTML] Outcomes for people with tuberculosis in the United States 1917–1948 by disease severity at presentation
SV Leavitt, CA Rodriguez, TC Bouton… - … journal of tuberculosis …, 2024 - ncbi.nlm.nih.gov
Background There is substantial heterogeneity in disease presentation for individuals with
tuberculosis disease, which may correlate with disease outcomes. We estimated disease …
tuberculosis disease, which may correlate with disease outcomes. We estimated disease …
Postinfectious Pulmonary Complications: Establishing Research Priorities to Advance the Field: An Official American Thoracic Society Workshop Report
Continued improvements in the treatment of pulmonary infections have paradoxically
resulted in a growing challenge of individuals with postinfectious pulmonary complications …
resulted in a growing challenge of individuals with postinfectious pulmonary complications …
[HTML][HTML] Flow cytometry-based method using diversity of cytokine production differentiates between Mycobacterium tuberculosis infection and disease
K Dolezalova, P Hadlova, M Ibrahimova, J Golias… - Tuberculosis, 2024 - Elsevier
Authors present a pilot study of the development of innovative flow cytometry-based assay
with a potential for use in tuberculosis diagnostics. Currently available tests do not provide …
with a potential for use in tuberculosis diagnostics. Currently available tests do not provide …
Multidrug-resistant tuberculosis
K Dheda, F Mirzayev, DM Cirillo, Z Udwadia… - Nature Reviews …, 2024 - nature.com
Tuberculosis (TB) remains the foremost cause of death by an infectious disease globally.
Multidrug-resistant or rifampicin-resistant TB (MDR/RR-TB; resistance to rifampicin and …
Multidrug-resistant or rifampicin-resistant TB (MDR/RR-TB; resistance to rifampicin and …
[HTML][HTML] Integrating molecular and radiological screening tools during community-based active case-finding for tuberculosis and COVID-19 in southern Africa
Objectives To evaluate diagnostic yield and feasibility of integrating testing for TB and
COVID-19 using molecular and radiological screening tools during community-based active …
COVID-19 using molecular and radiological screening tools during community-based active …
Finding the missed millions: innovations to bring tuberculosis diagnosis closer to key populations
Current strategies to promptly, effectively, and equitably screen people with tuberculosis
(TB) and link them to diagnosis and care are insufficient; new approaches are required to …
(TB) and link them to diagnosis and care are insufficient; new approaches are required to …