Obesity and heart failure with preserved ejection fraction: new insights and pathophysiological targets
BA Borlaug, MD Jensen, DW Kitzman… - Cardiovascular …, 2022 - academic.oup.com
Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …
intermingling epidemics driving perhaps the greatest unmet health problem in …
Myeloid cell derived IL1β contributes to pulmonary hypertension in HFpEF
BACKGROUND: Pulmonary hypertension (PH) in heart failure with preserved ejection
fraction (HFpEF) is a common and highly morbid syndrome, but mechanisms driving PH …
fraction (HFpEF) is a common and highly morbid syndrome, but mechanisms driving PH …
Pathophysiological insights into HFpEF from studies of human cardiac tissue
Heart failure with preserved ejection fraction (HFpEF) is a major, worldwide health-care
problem. Few therapies for HFpEF exist because the pathophysiology of this condition is …
problem. Few therapies for HFpEF exist because the pathophysiology of this condition is …
[HTML][HTML] Acetylation and phosphorylation changes to cardiac proteins in experimental HFpEF due to metabolic risk reveal targets for treatment
F Koser, AJ Hobbach, M Abdellatif, V Herbst, C Türk… - Life Sciences, 2022 - Elsevier
Aims Despite the high prevalence of heart failure with preserved ejection fraction (HFpEF),
the pathomechanisms remain elusive and specific therapy is lacking. Disease-causing …
the pathomechanisms remain elusive and specific therapy is lacking. Disease-causing …
A roadmap for therapeutic discovery in pulmonary hypertension associated with left heart failure. A scientific statement of the Heart Failure Association (HFA) of the …
P Ameri, V Mercurio, P Pollesello… - European journal of …, 2024 - Wiley Online Library
Pulmonary hypertension (PH) associated with left heart failure (LHF)(PH‐LHF) is one of the
most common causes of PH. It directly contributes to symptoms and reduced functional …
most common causes of PH. It directly contributes to symptoms and reduced functional …
Proteomic Pathways across Ejection Fraction Spectrum in Heart Failure: an EXSCEL Substudy
Background Ejection fraction (EF) is a key component of heart failure (HF) classification,
including the increasingly codified HF with mildly reduced EF (HFmrEF) category. However …
including the increasingly codified HF with mildly reduced EF (HFmrEF) category. However …
Myeloid Cell Derived IL1β Contributes to Pulmonary Vascular Remodeling in Heart Failure with Preserved Ejection Fraction
Background Pulmonary hypertension (PH) in heart failure with preserved ejection fraction
(HFpEF) is a common and highly morbid syndrome, but mechanisms driving PH-HFpEF are …
(HFpEF) is a common and highly morbid syndrome, but mechanisms driving PH-HFpEF are …