Depression predisposes to medical illnesses and advances biological aging indicated by
shorter telomere length, accelerated brain aging and advanced epigenetic aging. Medical …

Abstract Introduction The Cognitive Debt hypothesis proposes that repetitive negative
thinking (RNT), a modifiable process common to many psychological risk factors for …

Depression and Alzheimer's disease (AD) are substantial public health concerns. In the past
decades, a link between two disease entities has received extensive acknowledgment, yet …

Background: Depression is also common with older age. Alzheimer's disease (AD) studies
suggest that both cerebrospinal fluid and positron emission tomography (PET) amyloid …

Background: Depressive symptoms are common in older adults and associated with
increased morbidity and cognitive decline. These symptoms occur during preclinical and …

Aim Investigating what is underlying late‐life depression is becoming increasingly important
with the rapidly growing elderly population. Yet, the associations between plasma …

Late-life depression (LLD) is associated with a risk of developing Alzheimer's disease (AD).
However, the role of AD-pathophysiology in LLD, and its association with clinical symptoms …

The relationship between depressive disorders in the elderly and dementia, particularly
Alzheimer's disease (AD), is highly complex. While the nature of this relationship is still a …

Background: Depressive symptoms predict increased risk for dementia decades before the
emergence of cognitive symptoms. Studies in older adults provide preliminary evidence for …

Early detection of patients with late-life depression (LLD) with a high risk of developing
dementia contributes to early intervention. Odor identification (OI) dysfunction serves as a …