New strategies against drug resistance to herpes simplex virus

YC Jiang, H Feng, YC Lin, XR Guo - International journal of oral …, 2016 - nature.com
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a significant human
pathogen that results in mucocutaneous lesions in the oral cavity or genital infections …

[HTML][HTML] Application of aptamer-drug delivery system in the therapy of breast cancer

R Fan, X Tao, X Zhai, Y Zhu, Y Li, Y Chen… - Biomedicine & …, 2023 - Elsevier
Despite significant treatment advances, breast cancer remains the leading cause of cancer
death in women. From the current treatment situation, in addition to developing …

Hyaluronic-acid-tagged cubosomes deliver cytotoxics specifically to CD44-positive cancer cells

A Pramanik, Z Xu, N Ingram, PL Coletta… - Molecular …, 2022 - ACS Publications
Delivery of chemotherapy drugs specifically to cancer cells raises local drug doses in tumors
and therefore kills more cancer cells while reducing side effects in other tissues, thereby …

Review of the role of nanotechnology in overcoming the challenges faced in oral cancer diagnosis and treatment

VR Umapathy, PM Natarajan, B Swamikannu - Molecules, 2023 - mdpi.com
Throughout the world, oral cancer is a common and aggressive malignancy with a high risk
of morbidity, mortality, and recurrence. The importance of early detection in cancer …

pH-responsive dual-functional hydrogel integrating localized delivery and anti-cancer activities for highly effective therapy in PDX of OSCC

T Liu, Y Du, Y Yan, S Song, J Qi, X Xia, X Hu, Q Chen… - Materials Today, 2023 - Elsevier
As one of the most promising localized drug delivery systems for enhancing therapeutic
efficacy and reducing systemic toxicity, supramolecular hydrogels self-assembled from …

DNA-based nanomedicine with targeting and enhancement of therapeutic efficacy of breast cancer cells

Y Zhan, W Ma, Y Zhang, C Mao, X Shao… - … applied materials & …, 2019 - ACS Publications
Recently, a DNA tetrahedron has been reported to be a novel nanomedicine and promising
drug vector because of its compactness, biocompatibility, biosafety, and editability. Here, we …

Iron-doped cross-linked lipoic acid nano-aggregates for ferroptosis-mediated cancer treatment

J Tan, X Zhou, S Zhang - Acta Biomaterialia, 2023 - Elsevier
Recently, Fenton reaction-mediated ferroptosis has attracted great attention in cancer
treatment while the metabolism loss of iron and the limited endogenous H 2 O 2 level imped …

Dual-functional guanosine-based hydrogel integrating localized delivery and anticancer activities for cancer therapy

H Zhao, H Feng, J Liu, F Tang, Y Du, N Ji, L Xie… - Biomaterials, 2020 - Elsevier
Supramolecular hydrogel delivery systems have attracted widely attention owing to
incorporating various therapeutic agents in carriers to decrease unpredictable toxicities …

Nanomedicine, an emerging therapeutic strategy for oral cancer therapy

S Marcazzan, EM Varoni, E Blanco, G Lodi, M Ferrari - Oral oncology, 2018 - Elsevier
Oral cavity and oropharyngeal carcinomas (oral cancer) represents a significant cause of
morbidity and mortality. Despite efforts in improving early diagnosis and treatment, the 5 …

Improved tumor infiltration and immunomodulation for tumor therapy: a pathway based on tetrahedral framework nucleic acids coupled bacterial nanocells

Y Zhan, Y Zhang, C Mao, J Li, Y Zhao, Y Chen… - Nano Letters, 2022 - ACS Publications
Growing evidence indicates that the tumor microenvironment (TME) can be combined with
other therapeutic modalities, including cytotoxic chemotherapy and targeted therapies, to …