[HTML][HTML] Probing brain tissue microstructure with MRI: principles, challenges, and the role of multidimensional diffusion-relaxation encoding

B Lampinen, F Szczepankiewicz, J Lätt, L Knutsson… - NeuroImage, 2023 - Elsevier
Diffusion MRI uses the random displacement of water molecules to sensitize the signal to
brain microstructure and to properties such as the density and shape of cells. Microstructure …

[HTML][HTML] Neurite Exchange Imaging (NEXI): A minimal model of diffusion in gray matter with inter-compartment water exchange

IO Jelescu, A de Skowronski, F Geffroy, M Palombo… - NeuroImage, 2022 - Elsevier
Biophysical models of diffusion in white matter have been center-stage over the past two
decades and are essentially based on what is now commonly referred to as the “Standard …

[HTML][HTML] Reproducibility of the standard model of diffusion in white matter on clinical MRI systems

S Coelho, SH Baete, G Lemberskiy, B Ades-Aron… - NeuroImage, 2022 - Elsevier
Estimating intra-and extra-axonal microstructure parameters, such as volume fractions and
diffusivities, has been one of the major efforts in brain microstructure imaging with MRI. The …

Parameter estimation for WMTI‐Watson model of white matter using encoder–decoder recurrent neural network

Y Diao, I Jelescu - Magnetic Resonance in Medicine, 2023 - Wiley Online Library
Purpose Biophysical modeling of the diffusion MRI (dMRI) signal provides estimates of
specific microstructural tissue properties. Although non‐linear least squares (NLLS) is the …

Mapping tissue microstructure across the human brain on a clinical scanner with soma and neurite density image metrics

S Schiavi, M Palombo, D Zacà, F Tazza… - Human Brain …, 2023 - Wiley Online Library
Soma and neurite density image (SANDI) is an advanced diffusion magnetic resonance
imaging biophysical signal model devised to probe in vivo microstructural information in the …

A simulation-driven supervised learning framework to estimate brain microstructure using diffusion MRI

C Fang, Z Yang, D Wassermann, JR Li - Medical Image Analysis, 2023 - Elsevier
We propose a framework to train supervised learning models on synthetic data to estimate
brain microstructure parameters using diffusion magnetic resonance imaging (dMRI) …

ACID: A Comprehensive Toolbox for Image Processing and Modeling of Brain, Spinal Cord, and Ex Vivo Diffusion MRI Data

G David, B Fricke, JM Oeschger, L Ruthotto, FJ Fritz… - bioRxiv, 2023 - biorxiv.org
Diffusion MRI (dMRI) has become a crucial imaging technique in the field of neuroscience,
with a growing number of clinical applications. Although most studies still focus on the brain …

[HTML][HTML] Comparison of different neurite density metrics with brain asymmetry evaluation

II Maximov, LT Westlye - Zeitschrift für Medizinische Physik, 2023 - Elsevier
The standard diffusion MRI model with intra-and extra-axonal water pools offers a set of
microstructural parameters describing brain white matter architecture. However, non …

Anesthesia‐related brain microstructure modulations detected by diffusion magnetic resonance imaging

TB Lindhardt, CS Skoven, L Bordoni… - NMR in …, 2024 - Wiley Online Library
Recent studies have shown significant changes to brain microstructure during sleep and
anesthesia. In vivo optical microscopy and magnetic resonance imaging (MRI) studies have …

[HTML][HTML] Compartmental diffusion and microstructural properties of human brain gray and white matter studied with double diffusion encoding magnetic resonance …

H Lundell, C Najac, M Bulk, HE Kan, AG Webb… - Neuroimage, 2021 - Elsevier
Double diffusion encoding (DDE) of the water signal offers a unique ability to separate the
effect of microscopic anisotropic diffusion in structural units of tissue from the overall …