Role of oxidative stress in epileptic seizures

EJ Shin, JH Jeong, YH Chung, WK Kim, KH Ko… - Neurochemistry …, 2011 - Elsevier
Oxidative stress resulting from excessive free-radical release is likely implicated in the
initiation and progression of epilepsy. Therefore, antioxidant therapies aimed at reducing …

Mitochondria, oxidative stress, and temporal lobe epilepsy

S Waldbaum, M Patel - Epilepsy research, 2010 - Elsevier
Mitochondrial oxidative stress and dysfunction are contributing factors to various
neurological disorders. Recently, there has been increasing evidence supporting the …

Mitochondrial dysfunction and oxidative stress: a contributing link to acquired epilepsy?

S Waldbaum, M Patel - Journal of bioenergetics and biomembranes, 2010 - Springer
Mitochondrial dysfunction and oxidative stress contribute to several neurologic disorders
and have recently been implicated in acquired epilepsies such as temporal lobe epilepsy …

Modulation of oxidative stress and mitochondrial function by the ketogenic diet

J Milder, M Patel - Epilepsy research, 2012 - Elsevier
The ketogenic diet (KD) is a high-fat, low carbohydrate diet that is used as a therapy for
intractable epilepsy. However, the mechanism (s) by which the KD achieves neuroprotection …

Mitochondrial dysfunction in epilepsy

J Folbergrová, WS Kunz - Mitochondrion, 2012 - Elsevier
Mitochondrial dysfunction has been identified as one potential cause of epileptic seizures.
Impaired mitochondrial function has been reported for the seizure focus of patients with …

The role of reactive species in epileptogenesis and influence of antiepileptic drug therapy on oxidative stress

B Martinc, I Grabnar, T Vovk - Current Neuropharmacology, 2012 - ingentaconnect.com
Epilepsy is considered one of the most common neurological disorders. The focus of this
review is the acquired form of epilepsy, with the development process consisting of three …

The Neuroprotective Effect of Curcumin and Nigella sativa Oil Against Oxidative Stress in the Pilocarpine Model of Epilepsy: A Comparison with Valproate

HS Aboul Ezz, YA Khadrawy, NA Noor - Neurochemical research, 2011 - Springer
Oxidative stress has been implicated to play a role in epileptogenesis and pilocarpine-
induced seizures. The present study aims to evaluate the antioxidant effects of curcumin …

The Antioxidant Effect of Medicago sativa L. (Alfalfa) Ethanolic Extract against Mercury Chloride (HgCl2) Toxicity in Rat Liver and Kidney: An In Vitro and In Vivo …

M Raeeszadeh, M Moradi, P Ayar… - Evidence‐Based …, 2021 - Wiley Online Library
Heavy metals such as mercury are some of the environmental pollutants and can induce
toxicity by bioaccumulation and oxidative damage. This study aimed to investigate the effect …

Impairments in oxidative glucose metabolism in epilepsy and metabolic treatments thereof

T McDonald, M Puchowicz, K Borges - Frontiers in Cellular …, 2018 - frontiersin.org
There is mounting evidence that oxidative glucose metabolism is impaired in epilepsy and
recent work has further characterized the metabolic mechanisms involved. In healthy people …

Dose-dependent effects of cobalt nanoparticles on antioxidant systems, hematological parameters, and organ morphology in albino mice

A Umar, MS Khan, M Wajid, MU Khan - BioNanoScience, 2024 - Springer
The present study was aimed to understand the dose-dependent effects of cobalt carbonate
nanoparticles (CoCO3 NPs), impacts on the antioxidant systems, hematological parameters …