High-quality evidence shows that MRI in biopsy-naive men can reduce the number of men
who need prostate biopsy and can reduce the number of diagnoses of clinically insignificant …

Background There is uncertainty in deferred active treatment (DAT) programmes, regarding
patient selection, follow-up and monitoring, reclassification, and which outcome measures …

Purpose: The summary presented herein represents Part I of the three-part series dedicated
to Clinically Localized Prostate Cancer: AUA/ASTRO Guideline, discussing risk assessment …

Abstract Context The Prostate Imaging-Reporting and Data System (PI-RADS) v2 analysis
system for multiparametric magnetic resonance imaging (mpMRI) detection of prostate …

Background Active surveillance (AS) is the preferred management option for most men with
grade group (GG) 1 prostate cancer (PCa). Questions persist regarding long-term outcomes …

The definition of clinically significant prostate cancer is a dynamic process that was initiated
many decades ago, when there was already evidence that a great proportion of patients with …

Results The final selected studies (n= 24 studies; 32,715 patients) showed significant
reductions in ICU admission (OR= 0.78, 95% CI: 0.58–1.06; n= 10; I 2= 58.5%) and death …

Although prostate cancer (PCa) is the most commonly diagnosed cancer in men, most
patients do not die from the disease. Prostate specific antigen (PSA), the most widely used …

Active surveillance (AS) represents a well-recognized management option for many patients
with low-and very low-risk prostate cancer (PCa). AS aims to reduce overtreatment whilst …

In response to the rising incidence of indolent, low-risk prostate cancer (PCa) due to
increased prostate-specific antigen (PSA) screening in the 1990s, active surveillance (AS) …