Peroxisome proliferator–activated receptor α (PPAR α) is a nuclear receptor of clinical
interest as a drug target in various metabolic disorders. PPAR α also exhibits marked anti …

Background Results from observational and genetic epidemiological studies suggest that
lower serum homocysteine levels are associated with lower incidence of cardiovascular …

The aim of this updated statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of stroke among individuals who have not previously …

Abstract The National Kidney Foundation's Kidney Disease Outcomes Quality Initiative
(KDOQI) has provided evidence-based guidelines for nutrition in kidney diseases since …

Background and Purpose—This guideline provides an overview of the evidence on
established and emerging risk factors for stroke to provide evidence-based …

Objective To assess the efficacy of vitamin and antioxidant supplements in the prevention of
cardiovascular diseases. Design Meta-analysis of randomised controlled trials. Data …

High level of homocysteine (hyperhomocysteinemia, HHcy) is associated with increased risk
for vascular disease. Evidence for this emerges from epidemiological studies which show …

Background The efficacy of treatments that lower homocysteine concentrations in reducing
the risk of cardiovascular disease remains controversial. Our aim was to do a meta-analysis …

Summary Background The MTHFR 677C→ T polymorphism has been associated with
raised homocysteine concentration and increased risk of stroke. A previous overview …

Background Patients undergoing dialysis have a substantially increased risk of
cardiovascular mortality and morbidity. Although several trials have shown the …