Many studies show that glucose metabolism in epileptic brain areas can be impaired.
Energy is crucial to maintain normal brain function, including ion and neurotransmitter …

Epilepsy is a common neurological disease in both humans and domestic dogs, making
dogs an ideal translational model of epilepsy. In both species, epilepsy is a complex brain …

Life expectancy of humans has increased continuously up to the present days, but their
health status (healthspan) was not enhanced by similar extent. To decrease enormous …

Epilepsy is a challenging multifactorial disorder with a complex genetic background. Our
current understanding of the pathophysiology and treatment of epilepsy has substantially …

Circadian and other physiological rhythms play a key role in both normal homeostasis and
disease processes. Such is the case of circadian and infradian seizure patterns observed in …

Introduction The effect of medium-chain fatty acid-containing triglycerides (MCT), long-chain
polyunsaturated fatty acid-containing triglycerides from fish oil (FO), and their combination …

Drug resistance continues to be a major clinical problem in the therapeutic management of
canine epilepsies with substantial implications for quality of life and survival times …

It is now widely accepted that ketosis (a physiological state characterized by elevated
plasma ketone body levels) possesses a wide range of neuroprotective effects. There is a …

Psychiatric and cognitive comorbidities have been known to play a major role in human
epilepsy for a long time. People with epilepsy (PWE) frequently express signs of varying …

Objective Cognitive impairments (CI) have recently been identified in canine epilepsy
patients. A medium-chain triglyceride (MCT) enriched diet has been demonstrated to …