Compounds incorporating guanidine moieties constitute a versatile class of biologically
interesting molecules with a wide array of applications. As such, guanidines have been …

Diabetes mellitus (DM) is a major metabolic disorder due to hyperglycemia, which is
increasing all over the world. From the last two decades, the use of synthetic agents has …

The pyrimidine scaffold represents one of the privileged structures in chemistry, and there
has been an increase in number of studies utilizing this scaffold and its derivatives. The …

A series of new 2-amino-4-aryl-6-pyridopyrimidines, and their N-alkyl bromide derivatives
were designed and synthesized by employing methyl substituted azachalcones. These …

A series of spirooxindolo-pyrrolidines, pyrrolizidines, and pyrrolothiazoles hybrid
compounds were prepared in good yields by regioselective, three-component, 1, 3-dipolar …

We describe here the synthesis of dihydropyrimidines derivatives 3a–p, and evaluation of
their α-glucosidase enzyme inhibition activities. Compounds 3b (IC 50= 62.4±1.5 μM), 3c (IC …

A synthetic strategy to access small libraries of triazolylmethoxy chalcones 4 {1–20},
triazolylmethoxy flavanones 5 {1–10} and triazolylmethoxy aminopyrimidines 6 {1–17} from …

A convenient and efficient new method has been established for the synthesis of
dihydropyrimidines by inexpensive and non-toxic N-acetyl glycine (NAG) catalysed reaction …

A new series of tetrahydro-quinazoline and tetrahydro-1H-dibenzo [b, e][1, 4] diazepine
analogs were synthesized and tested for their DHFR inhibition and in vitro antitumor activity …

An in vitro antidiabetic activity on α‐amylase and α–glucosidase activity of novel 10‐chloro‐
4‐(2‐chlorophenyl)‐12‐phenyl‐5, 6‐dihydropyrimido [4, 5‐a] acridin‐2‐amines (3a–3f) …