Bioorthogonal chemistry represents a class of high-yielding chemical reactions that proceed
rapidly and selectively in biological environments without side reactions towards …

Molecular changes in malignant tissue can lead to an increase in the expression levels of
various proteins or receptors that can be used to target the disease. In oncology, diagnostic …

Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

The study of carbon-based nanomaterials (CBNs) for biomedical applications has attracted
great attention due to their unique chemical and physical properties including thermal …

With growing interest, a large number of researches have been conducted on carbon-based
nanomaterials (CBNs). However, their uses are limited due to comprehensive potential …

Over the past decade, theranostic imaging has emerged as a powerful clinical tool in
oncology for identifying patients likely to respond to targeted therapies and for monitoring …

The advent of click chemistry has had a profound influence on almost all branches of
chemical science. This is particularly true of radiochemistry and the synthesis of agents for …

Pretargeted nuclear imaging and radiotherapy have recently attracted increasing attention
for diagnosis and treatment of cancer with nanomedicines. This is because it conceptually …

The use of a bioorthogonal reaction for the selective cleavage of tumor-bound antibody–
drug conjugates (ADCs) would represent a powerful new tool for ADC therapy, as it would …

The development of highly selective and fast biocompatible reactions for ligation and
cleavage has paved the way for new diagnostic and therapeutic applications of pretargeted …