Definition, causes, pathogenesis, and consequences of chronic obstructive pulmonary disease exacerbations
AI Ritchie, JA Wedzicha - Clinics in chest medicine, 2020 - chestmed.theclinics.com
Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) are episodes of
symptom worsening 1 that have significant adverse consequences for patients. 2 The …
symptom worsening 1 that have significant adverse consequences for patients. 2 The …
Chronic obstructive pulmonary disease exacerbation fundamentals: diagnosis, treatment, prevention and disease impact
In chronic obstructive pulmonary disease (COPD), exacerbations (ECOPD), characterized
by an acute deterioration in respiratory symptoms, are fundamental events impacting …
by an acute deterioration in respiratory symptoms, are fundamental events impacting …
[HTML][HTML] An updated definition and severity classification of chronic obstructive pulmonary disease exacerbations: the Rome proposal
Over 200 years ago, René Laennec published the first description of emphysema, an
important pathobiological element of what is today known as chronic obstructive pulmonary …
important pathobiological element of what is today known as chronic obstructive pulmonary …
The role of the microbiome in exacerbations of chronic lung diseases
Culture-independent microbiological techniques have shown a previously unappreciated
complexity to the bacterial microbiome of the respiratory tract that forces reconsideration of …
complexity to the bacterial microbiome of the respiratory tract that forces reconsideration of …
Cellular and molecular mechanisms of chronic obstructive pulmonary disease
PJ Barnes - Clinics in chest medicine, 2014 - chestmed.theclinics.com
Chronic obstructive pulmonary disease (COPD) involves chronic inflammation of the lung,
particularly in peripheral airways and parenchyma, which increases during acute …
particularly in peripheral airways and parenchyma, which increases during acute …
Acute exacerbations and lung function loss in smokers with and without chronic obstructive pulmonary disease
MT Dransfield, KM Kunisaki, MJ Strand… - American journal of …, 2017 - atsjournals.org
Rationale: Acute exacerbations of chronic obstructive pulmonary disease (COPD) increase
the risk of death and drive healthcare costs, but whether they accelerate loss of lung function …
the risk of death and drive healthcare costs, but whether they accelerate loss of lung function …
Systemic manifestations and comorbidities of COPD
Increasing evidence indicates that chronic obstructive pulmonary disease (COPD) is a
complex disease involving more than airflow obstruction. Airflow obstruction has profound …
complex disease involving more than airflow obstruction. Airflow obstruction has profound …
[HTML][HTML] COPD exacerbations: defining their cause and prevention
JA Wedzicha, TAR Seemungal - The lancet, 2007 - thelancet.com
Exacerbations of chronic obstructive pulmonary disease (COPD) are episodes of worsening
of symptoms, leading to substantial morbidity and mortality. COPD exacerbations are …
of symptoms, leading to substantial morbidity and mortality. COPD exacerbations are …
[HTML][HTML] Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic …
Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …
[HTML][HTML] Mechanisms and impact of the frequent exacerbator phenotype in chronic obstructive pulmonary disease
JA Wedzicha, SE Brill, JP Allinson, GC Donaldson - BMC medicine, 2013 - Springer
Exacerbations of chronic obstructive pulmonary disease (COPD) are important events that
carry significant consequences for patients. Some patients experience frequent …
carry significant consequences for patients. Some patients experience frequent …