Patients with disseminated colorectal cancer have a dismal prognosis with a 5-year survival
rate of only 13%. In order to identify new treatment modalities and new targets, we searched …

The epidermis, outermost layer of the skin, is constantly renewing itself through proliferative
and differentiation processes. These processes are vital to maintain proper epidermal …

Gastric cancer (GC) is a highly heterogeneous, complex disease and the fifth most common
cancer worldwide (about 1 million cases and 784,000 deaths worldwide in 2018). GC has a …

Introduction: Cannabis sativa is utilized mainly for palliative care worldwide. Ovarian cancer
(OC) is a lethal gynecologic cancer. A particular cannabis extract fraction ('F7′) and the …

The LIM protein Ajuba has been implicated in the development of human cancers. To date,
its expression pattern and biological significance in breast cancers (BC) have not been fully …

Ajuba is a multiple LIM domain‐containing protein and functions as a transcriptional
coregulator to modulate many gene expressions in various cellular processes. Here, we …

NTRK fusions are validated oncogenic drivers of various adult and pediatric tumor types,
including thyroid cancer, and serve as a therapeutic target. Recently, tropomyosin receptor …

LIM protein‐domain containing protein Ajuba (encoded by AJUBA) functions as a scaffold
protein to regulate protein–protein interactions, signalling transduction and genes …

The LIM‐domain protein Ajuba is associated with cell proliferation, a fundamental process of
tissue regeneration and cancer. We report that in the liver, Ajuba expression is increased …

Purpose: The LIM (Lin-11, Isl1, MEC-3) domain protein AJUBA is involved in multiple
biological functions, and its aberrant expression is related to the occurrence and …