The rapidly declining prevalence of Helicobacter pylori infection and widespread use of
potent anti-secretory drugs means peptic ulcer disease has become substantially less …

Iron is an essential micronutrient for a myriad of physiological processes in the body beyond
erythropoiesis. Iron deficiency (ID) is a common comorbidity in patients with heart failure …

Peptic ulcer disease (PUD) is a common condition that both primary care providers and
gastroenterologists encounter. Symptoms of peptic ulcer disease are variable and may …

Background There are several guidelines addressing the issues around the use of NSAIDs.
However, none has specifically addressed the upper versus lower gastrointestinal (GI) risk …

Background Transfusion thresholds for acute upper gastrointestinal bleeding are
controversial. So far, only three small, underpowered studies and one single-centre trial …

Non-variceal upper gastrointestinal bleeding (NVUGIB) is bleeding that develops in the
oesophagus, stomach or proximal duodenum. Peptic ulcers, caused by Helicobacter pylori …

Introduction Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most prescribed
pharmacological groups, especially in elderly patients. Areas Covered The main GI and CV …

UGIB is predominantly nonvariceal in origin and remains one of the most common
challenges faced by gastroenterologists and endoscopists in daily clinical practice. Despite …

Recent studies have shown that liver cirrhosis (LC) behaves as an acquired
hypercoagulable state with increased thrombotic risk. This is why anticoagulation therapy …

Non-steroidal anti-inflammatory drug (NSAID) use increases the risk of gastrointestinal
complications such as ulcers or bleeding. The presence of factors like advanced age, history …