To cite this article: Liu J, Bian Z, Kuijpers‐Jagtman AM, Von den Hoff JW: Skin and oral
mucosa equivalents: construction and performance Orthod Craniofac Res 2010; 13: 11–20 …

Oral mucosa consists of two tissue layers, the superficial epithelium and the underlying
lamina propria. Together, oral mucosa functions as a barrier against exogenous substances …

A problem maxillofacial surgeons face is a lack of sufficient autogenous oral mucosa for
reconstruction of the oral cavity. Split-thickness or oral mucosa grafts require more than one …

Background: Current organotypic models of dysplasia and oral squamous cell carcinoma
(OSCC) lack the complexity that mimics in vivo tissue. Here we describe a three-dimensional …

The cutaneous basement membrane (BM) plays an important role in normal and
pathological conditions. However, few studies have addressed the formation of the …

The connective tissue is known to have a general supportive effect for the development of
the overlying epithelium; however, the more specific effects of fibroblasts and the …

Background: Numerous epidemiological studies have reported that tobacco smoking is a
major risk factor for oral cancer, but relatively little is known about the effect of nicotine, a …

Different epithelia show extensive variation in differentiation. Epidermis and epithelium from
the hard palate are both typical examples of orthokeratinized epithelia whereas buccal …

Photoaged skin contains elastotic materials in the upper reticular dermis. This phenomenon
is commonly known as solar elastosis. Little is known about the mechanisms leading to the …

Epidermis reconstructed on de-epidermized dermis (RE-DED) and on fibroblast-populated
collagen matrix (Living Skin Equivalent) showed a histologic resemblance to native …