All patients with asthma are at risk of having exacerbations. Hospitalizations and emergency
department (ED) visits account for a large proportion of the health-care cost burden of …

Acute severe asthma remains a major economic and health burden. The natural history of
acute decompensations is one of resolution and only about 0.4% of patients succumb …

Building on the success of the 14 previous editions, this remarkable reference has been
extensively reorganized and expanded and now comprises almost 1,500 individual drug …

About 10% of American children have asthma, and its prevalence, morbidity, and mortality
have been increasing. Asthma is an inflammatory disease with edema, bronchial …

Publisher Summary This chapter provides background information on the implications of
stereochemistry for drug action and disposition. It focuses on the principles involved and …

Covering every essential element in the development of chiral products, this reference
provides a solid overview of the formulation, biopharmaceutical characteristics, and …

In this article, studies that have examined the effects on morbidity and mortality of β-agonist
drugs are reviewed. With regard to morbidity, there is considerable evidence that the regular …

Written action plans are effective within asthma self-management, but there are few
guidelines about the specific medication adjustments which can be recommended for self …

Background: Limited dose-response information is available for nebulized β2-agonists,
especially in young children. Objective: The purpose of this study was to determine the …

The presence of acute reversibility to bronchodilators does not distinguish asthma from
COPD. Patients with either condition can benefit from bronchodilators, and should be given …