Asymmetric organocatalysis: an enabling technology for medicinal chemistry
B Han, XH He, YQ Liu, G He, C Peng… - Chemical Society Reviews, 2021 - pubs.rsc.org
The efficacy and synthetic versatility of asymmetric organocatalysis have contributed
enormously to the field of organic synthesis since the early 2000s. As asymmetric …
enormously to the field of organic synthesis since the early 2000s. As asymmetric …
Bifunctional amine‐squaramides: powerful hydrogen‐bonding organocatalysts for asymmetric domino/cascade reactions
P Chauhan, S Mahajan, U Kaya… - … Synthesis & Catalysis, 2015 - Wiley Online Library
Organocatalytic domino/cascade reactions provide a convenient method for the construction
of complex molecular structures bearing multiple stereocenters in a highly stereoselective …
of complex molecular structures bearing multiple stereocenters in a highly stereoselective …
Squaramide‐catalyzed asymmetric reactions
BL Zhao, JH Li, DM Du - The Chemical Record, 2017 - Wiley Online Library
Bifunctional squaramides have emerged as powerful hydrogen‐bonding catalysts for
promoting a wide array of useful asymmetric reactions, which provides convenient methods …
promoting a wide array of useful asymmetric reactions, which provides convenient methods …
Enantioselective Synthesis of AG‐041R by using N‐Heteroarenesulfonyl Cinchona Alkaloid Amides as Organocatalysts
N Hara, S Nakamura, M Sano, R Tamura… - … A European Journal, 2012 - Wiley Online Library
The organocatalytic enantioselective decarboxylative addition of malonic acid half thioesters
to ketimines derived from isatins by using N‐heteroarenesulfonyl cinchona alkaloid amides …
to ketimines derived from isatins by using N‐heteroarenesulfonyl cinchona alkaloid amides …
Stereoselective reactions of nitro compounds in the synthesis of natural compound analogs and active pharmaceutical ingredients
AY Sukhorukov, AA Sukhanova, SG Zlotin - Tetrahedron, 2016 - Elsevier
Nitroalkanes and nitroalkenes have been always considered as convenient and readily
available intermediates in organic synthesis, including total synthesis of natural products. 1 …
available intermediates in organic synthesis, including total synthesis of natural products. 1 …
Catalytic enantioselective decarboxylative reactions using organocatalysts
S Nakamura - Organic & Biomolecular Chemistry, 2014 - pubs.rsc.org
Catalytic decarboxylative reactions are attractive as biomimetic reactions and
environmentally friendly reaction processes. In this review, the origin and recent …
environmentally friendly reaction processes. In this review, the origin and recent …
Membrane-grafted asymmetric organocatalyst for an integrated synthesis–separation platform
In this work we introduce a sustainable membrane-based synthesis–separation platform for
enantioselective organocatalysis. An azido derivatized cinchona-squaramide bifunctional …
enantioselective organocatalysis. An azido derivatized cinchona-squaramide bifunctional …
Recent advances in catalytic asymmetric decarboxylative addition reactions
ZL Wang - Advanced Synthesis & Catalysis, 2013 - Wiley Online Library
This review examines recent advances in asymmetric catalytic decarboxylative addition
reactions which have become a powerful method to form C C and C X bond using …
reactions which have become a powerful method to form C C and C X bond using …
Unprecedented hydrophobic amplification in noncovalent organocatalysis “on water”: hydrophobic chiral squaramide catalyzed Michael addition of malonates to …
In this study, water was demonstrated to be an exceptionally efficient reaction medium for
the noncovalent, hydrogen-bonding-promoted enantioselective Michael addition of …
the noncovalent, hydrogen-bonding-promoted enantioselective Michael addition of …
Hydrogen-bond-mediated cascade reaction involving chalcones: Facile synthesis of enantioenriched trisubstituted tetrahydrothiophenes
A bifunctional squaramide catalyzed sulfa-Michael/aldol cascade reaction between 1, 4-
dithiane-2, 5-diol and chalcones with a low catalyst loading has been developed …
dithiane-2, 5-diol and chalcones with a low catalyst loading has been developed …