Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-Mycobacterium tuberculosis Strains

HMA Hameed, MM Islam, C Chhotaray… - Frontiers in cellular …, 2018 - frontiersin.org
Tuberculosis (TB) is a formidable infectious disease that remains a major cause of death
worldwide today. Escalating application of genomic techniques has expedited the …

The epidemiological importance of subclinical tuberculosis. A critical reappraisal

EA Kendall, S Shrestha, DW Dowdy - American journal of …, 2021 - atsjournals.org
From Chlamydia (1) to malaria (2) to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2)(3), it is increasingly recognized that individuals without recognizable …

Does tuberculosis threaten our ageing populations?

R Byng-Maddick, M Noursadeghi - BMC infectious diseases, 2016 - Springer
Background The global population is ageing quickly and our understanding of age-related
changes in the immune system suggest that the elderly will have less immunological …

Tuberculosis in an aging world

AM Olmo-Fontánez, J Turner - Pathogens, 2022 - mdpi.com
Tuberculosis (TB) is one of the leading causes of death due to its being an infectious
disease, caused by the airborne pathogen Mycobacterium tuberculosis (M. tb) …

[HTML][HTML] Tackling two pandemics: a plea on World Tuberculosis Day

T Wingfield, LE Cuevas, P MacPherson… - The Lancet …, 2020 - ncbi.nlm.nih.gov
We are facing an unprecedented pandemic. A quarter of the world's population is infected
and, between 2020 and 2021, it is predicted that 10 million people will have fallen ill, 3 …

Tuberculosis in older adults: case studies from four countries with rapidly ageing populations in the western pacific region

AKJ Teo, K Rahevar, F Morishita, A Ang… - BMC Public Health, 2023 - Springer
Abstract Background The Western Pacific Region has one of the fastest-growing populations
of older adults (≥ 65 years) globally, among whom tuberculosis (TB) poses a particular …

Spatio-temporal variation in tuberculosis incidence and risk factors for the disease in a region of unbalanced socio-economic development

L Wang, C Xu, M Hu, J Qiao, W Chen, T Li, S Qian… - BMC Public Health, 2021 - Springer
Background Previous research pointed to a close relationship between the incidence of
tuberculosis (TB) in aging populations and socio-economic conditions, however there has …

Tuberculosis in the elderly: Why inflammation matters

TJ Piergallini, J Turner - Experimental gerontology, 2018 - Elsevier
Growing old is associated with an increase in the basal inflammatory state of an individual
and susceptibility to many diseases, including infectious diseases. Evidence is growing to …

Spatial pattern of tuberculosis (TB) and related socio-environmental factors in South Korea, 2008-2016

C Im, Y Kim - PLoS One, 2021 - journals.plos.org
Tuberculosis (TB) incidence and corresponding mortality rates in S. Korea are unusual and
unique compared to other economically developed countries. Korea has the highest TB …

Time to diagnosis of tuberculosis is greater in older patients: a retrospective cohort review

A Abbara, SM Collin, OM Kon, K Buell… - ERJ open …, 2019 - Eur Respiratory Soc
Introduction Age-related immunosenescence influences the presentation of tuberculosis
(TB) in older patients. Here, we explore the clinical and radiological presentation of TB in the …