Clinical progress and advanced research of red blood cells based drug delivery system
Y Li, F Raza, Y Liu, Y Wei, R Rong, M Zheng, W Yuan… - Biomaterials, 2021 - Elsevier
Red blood cells (RBCs) are biocompatible carriers that can be employed to deliver different
bioactive substances. In the past few decades, many strategies have been developed to …
bioactive substances. In the past few decades, many strategies have been developed to …
Accumulation of cytoplasmic DNA due to ATM deficiency activates the microglial viral response system with neurotoxic consequences
X Song, F Ma, K Herrup - Journal of Neuroscience, 2019 - Soc Neuroscience
ATM (ataxia-telangiectasia mutated) is a PI3K-like kinase best known for its role in the DNA
damage response (DDR), especially after double-strand breaks. Mutations in the ATM gene …
damage response (DDR), especially after double-strand breaks. Mutations in the ATM gene …
NAD+ supplementation prevents STING‐induced senescence in ataxia telangiectasia by improving mitophagy
Senescence phenotypes and mitochondrial dysfunction are implicated in aging and in
premature aging diseases, including ataxia telangiectasia (A‐T). Loss of mitochondrial …
premature aging diseases, including ataxia telangiectasia (A‐T). Loss of mitochondrial …
Drug-loaded erythrocytes: on the road toward marketing approval
Erythrocyte drug encapsulation is one of the most promising therapeutic alternative
approaches for the administration of toxic or rapidly cleared drugs. Drug-loaded erythrocytes …
approaches for the administration of toxic or rapidly cleared drugs. Drug-loaded erythrocytes …
Ataxia-telangiectasia: future prospects
MW Chaudhary, RS Al-Baradie - The application of clinical …, 2014 - Taylor & Francis
Ataxia-telangiectasia (AT) is an autosomal recessive multi-system disorder caused by
mutation in the ataxia-telangiectasia mutated gene (ATM). ATM is a large serine/threonine …
mutation in the ataxia-telangiectasia mutated gene (ATM). ATM is a large serine/threonine …
Inflammation, a significant player of Ataxia–Telangiectasia pathogenesis?
Abstract Introduction Ataxia–Telangiectasia (AT) syndrome is an autosomal recessive
neurodegenerative disorder characterized by cerebellar ataxia, oculocutaneous …
neurodegenerative disorder characterized by cerebellar ataxia, oculocutaneous …
Leishmania infantum Induces Mild Unfolded Protein Response in Infected Macrophages
The Leishmaniases are a group of parasitic diseases caused by protozoa of the Leishmania
genus affecting both humans and other vertebrates. Leishmania is an intracellular pathogen …
genus affecting both humans and other vertebrates. Leishmania is an intracellular pathogen …
Ataxia telangiectasia
A Nissenkorn, B Ben-Zeev - Handbook of clinical neurology, 2015 - Elsevier
Ataxia telangiectasia (AT) is an autosomal recessive multisystem genetic disorder caused by
a mutation in the ATM gene encoding for the ATM protein. AT systemic manifestations …
a mutation in the ATM gene encoding for the ATM protein. AT systemic manifestations …
Dexamethasone improves redox state in ataxia telangiectasia cells by promoting an NRF2‐mediated antioxidant response
S Biagiotti, M Menotta, S Orazi, C Spapperi… - The FEBS …, 2016 - Wiley Online Library
Ataxia telangiectasia (A‐T) is a rare incurable neurodegenerative disease caused by
biallelic mutations in the gene for ataxia‐telangiectasia mutated (ATM). The lack of a …
biallelic mutations in the gene for ataxia‐telangiectasia mutated (ATM). The lack of a …