Cannabis use and cannabis use disorder
Cannabis use disorder (CUD) is an underappreciated risk of using cannabis that affects~
10% of the 193 million cannabis users worldwide. The individual and public health burdens …
10% of the 193 million cannabis users worldwide. The individual and public health burdens …
Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies
Objective To systematically assess credibility and certainty of associations between
cannabis, cannabinoids, and cannabis based medicines and human health, from …
cannabis, cannabinoids, and cannabis based medicines and human health, from …
Cannabis and synaptic reprogramming of the developing brain
Recent years have been transformational in regard to the perception of the health risks and
benefits of cannabis with increased acceptance of use. This has unintended …
benefits of cannabis with increased acceptance of use. This has unintended …
THC and CBD: Similarities and differences between siblings
N Stella - Neuron, 2023 - cell.com
Summary Δ 9-tetrahydrocannabinol (THC) and its sibling, cannabidiol (CBD), are produced
by the same Cannabis plant and have similar chemical structures but differ dramatically in …
by the same Cannabis plant and have similar chemical structures but differ dramatically in …
Pharmacokinetic, behavioral, and brain activity effects of Δ9-tetrahydrocannabinol in adolescent male and female rats
CM Ruiz, A Torrens, E Castillo, CR Perrone… - …, 2021 - nature.com
Abstract Δ9-tetrahydrocannabinol (THC) is the intoxicating constituent of cannabis and is
responsible for the drug's reinforcing effects. Retrospective human studies suggest that …
responsible for the drug's reinforcing effects. Retrospective human studies suggest that …
THC and CBD: villain versus hero? Insights into adolescent exposure
Cannabis is the most used drug of abuse worldwide. It is well established that the most
abundant phytocannabinoids in this plant are Δ9-tetrahydrocannabinol (THC) and …
abundant phytocannabinoids in this plant are Δ9-tetrahydrocannabinol (THC) and …
Cannabis use, abuse, and withdrawal: Cannabinergic mechanisms, clinical, and preclinical findings
AJ Kesner, DM Lovinger - Journal of neurochemistry, 2021 - Wiley Online Library
Cannabis sativa is the most widely used illicit drug in the world. Its main psychoactive
component is delta‐9‐tetrahydrocannabinol (THC), one of over 100 phytocannabinoid …
component is delta‐9‐tetrahydrocannabinol (THC), one of over 100 phytocannabinoid …
Pharmacokinetic and pharmacodynamic properties of aerosolized (“vaped”) THC in adolescent male and female rats
Rationale Adolescent exposure to∆ 9-tetrahydrocannabinol (THC), the psychotropic
constituent of cannabis, might affect brain development, and in rodent models leads to long …
constituent of cannabis, might affect brain development, and in rodent models leads to long …
Adult consequences of repeated nicotine and Δ9-tetrahydrocannabinol (THC) vapor inhalation in adolescent rats
Rationale Use of electronic drug delivery systems (EDDS,“e-cigarettes”) to ingest nicotine
and Δ9-tetrahydrocannabinol (THC) has surged in adolescents in the USA; five times as …
and Δ9-tetrahydrocannabinol (THC) has surged in adolescents in the USA; five times as …
Dose mediates the protracted effects of adolescent THC exposure on reward and stress reactivity in males relevant to perturbation of the basolateral amygdala …
JMN Ferland, RJ Ellis, G Rompala, JA Landry… - Molecular …, 2023 - nature.com
Despite the belief that cannabis is relatively harmless, exposure during adolescence is
associated with increased risk of developing several psychopathologies in adulthood. In …
associated with increased risk of developing several psychopathologies in adulthood. In …