Methodological standards for the development and evaluation of clinical prediction rules: a review of the literature

LE Cowley, DM Farewell, S Maguire… - Diagnostic and prognostic …, 2019 - Springer
Clinical prediction rules (CPRs) that predict the absolute risk of a clinical condition or future
outcome for individual patients are abundant in the medical literature; however, systematic …

The accuracy of osteoporotic fracture risk prediction tools: a systematic review and meta-analysis

A Marques, RJO Ferreira, E Santos, E Loza… - Annals of the …, 2015 - ard.bmj.com
Objectives To identify and synthesise the best available evidence on the accuracy of the
currently available tools for predicting fracture risk. Methods We systematically searched …

Serum miRNA signatures are indicative of skeletal fractures in postmenopausal women with and without type 2 diabetes and influence osteogenic and adipogenic …

U Heilmeier, M Hackl, S Skalicky… - Journal of Bone and …, 2016 - academic.oup.com
Standard DXA measurements, including Fracture Risk Assessment Tool (FRAX) scores,
have shown limitations in assessing fracture risk in Type 2 Diabetes (T2D), underscoring the …

Performance of predictive tools to identify individuals at risk of non-traumatic fracture: a systematic review, meta-analysis, and meta-regression

C Beaudoin, L Moore, M Gagné, L Bessette… - Osteoporosis …, 2019 - Springer
There is no consensus on which tool is the most accurate to assess fracture risk. The results
of this systematic review suggest that QFracture, Fracture Risk Assessment Tool (FRAX) with …

External validation and comparison of three prediction tools for risk of osteoporotic fractures using data from population based electronic health records: retrospective …

N Dagan, C Cohen-Stavi, M Leventer-Roberts… - Bmj, 2017 - bmj.com
Objective To directly compare the performance and externally validate the three most
studied prediction tools for osteoporotic fractures—QFracture, FRAX, and Garvan—using …

The Belgian Bone Club 2020 guidelines for the management of osteoporosis in postmenopausal women

D Sanchez-Rodriguez, P Bergmann, JJ Body… - Maturitas, 2020 - Elsevier
Purpose To provide updated evidence-based guidelines for the management of
osteoporosis in postmenopausal women in Belgium. Methods The Belgian Bone Club (BBC) …

Systematic review and meta-analysis of the performance of clinical risk assessment instruments for screening for osteoporosis or low bone density

S Nayak, DL Edwards, AA Saleh… - Osteoporosis …, 2015 - Springer
We performed a systematic review and meta-analysis of the performance of clinical risk
assessment instruments for screening for DXA-determined osteoporosis or low bone …

Worldwide fracture prediction

GEH Fuleihan, M Chakhtoura, JA Cauley… - Journal of Clinical …, 2017 - Elsevier
The substantial increase in the burden of non-communicable diseases in general and
osteoporosis in particular, necessitates the establishment of efficient and targeted diagnosis …

[HTML][HTML] Composite outcomes in clinical prediction modeling: are we trying to predict apples and oranges?

K Dash, S Goodacre, L Sutton - Annals of Emergency Medicine, 2022 - Elsevier
Composite outcomes are widely used in clinical research. Existing literature has considered
the pros and cons of composite outcomes in clinical trials, but their extensive use in clinical …

COPD as an independent risk factor for osteoporosis and fractures

MG Adas-Okuma, SS Maeda, MR Gazzotti… - Osteoporosis …, 2020 - Springer
Fractures are common in individuals with COPD and occur at higher bone mass values than
expected. COPD appears to be an important risk factor for bone fragility. Introduction …