Therapeutic targets, novel drugs, and delivery systems for diabetes associated NAFLD and liver fibrosis
Type 2 diabetes mellitus (T2DM) associated non-alcoholic fatty liver disease (NAFLD) is the
fourth-leading cause of death. Hyperglycemia induces various complications, including …
fourth-leading cause of death. Hyperglycemia induces various complications, including …
Metabolic spectrum of liver failure in type 2 diabetes and obesity: from NAFLD to NASH to HCC
H Kim, DS Lee, TH An, HJ Park, WK Kim… - International journal of …, 2021 - mdpi.com
Liver disease is the spectrum of liver damage ranging from simple steatosis called as
nonalcoholic fatty liver disease (NAFLD) to hepatocellular carcinoma (HCC). Clinically …
nonalcoholic fatty liver disease (NAFLD) to hepatocellular carcinoma (HCC). Clinically …
Liraglutide attenuate central nervous inflammation and demyelination through AMPK and pyroptosis‐related NLRP3 pathway
Aims Multiple sclerosis (MS) still maintains increasing prevalence and poor prognosis, while
glucagon‐like peptide‐1 receptor (GLP‐1R) agonists show excellent neuroprotective …
glucagon‐like peptide‐1 receptor (GLP‐1R) agonists show excellent neuroprotective …
Alleviation of depression by glucagon-like peptide 1 through the regulation of neuroinflammation, neurotransmitters, neurogenesis, and synaptic function
Depression has emerged as a major cause of mortality globally. Many studies have reported
risk factors and mechanisms associated with depression, but it is as yet unclear how these …
risk factors and mechanisms associated with depression, but it is as yet unclear how these …
Temporal discounting as a candidate behavioral marker of obesity
WK Bickel, R Freitas-Lemos, DC Tomlinson… - Neuroscience & …, 2021 - Elsevier
Although obesity is a result of processes operating at multiple levels, most forms result from
decision-making behavior. The aim of this review was to examine the candidacy of temporal …
decision-making behavior. The aim of this review was to examine the candidacy of temporal …
A comprehensive review on weight loss associated with anti-diabetic medications
Obesity is a complex metabolic condition that can have a negative impact on one's health
and even result in mortality. The management of obesity has been addressed in a number of …
and even result in mortality. The management of obesity has been addressed in a number of …
Clinical impact of liraglutide as a treatment of obesity
H Alruwaili, B Dehestani… - … advances and applications, 2021 - Taylor & Francis
Obesity is defined as a chronic, complex, relapsing disease characterized by excessive
adipose tissue. Obesity impacts an individual's health by increasing complications such as …
adipose tissue. Obesity impacts an individual's health by increasing complications such as …
Metabolic dynamics of human Sertoli cells are differentially modulated by physiological and pharmacological concentrations of GLP-1
Obesity incidence has pandemic proportions and is expected to increase even further.
Glucagon-like peptide-1 (GLP-1) based therapies are well-established pharmacological …
Glucagon-like peptide-1 (GLP-1) based therapies are well-established pharmacological …
Molecular mechanisms controlled by mTOR in male reproductive system
In recent years, the mammalian target of rapamycin (mTOR) has emerged as a master
integrator of upstream inputs, such as amino acids, growth factors and insulin availability …
integrator of upstream inputs, such as amino acids, growth factors and insulin availability …
[HTML][HTML] Advances in anti-obesity pharmacotherapy: current treatments, emerging therapies, and challenges
Obesity is a major public health concern linked to health risks such as hypertension,
hyperlipidemia, type 2 diabetes mellitus (T2DM), stroke, metabolic syndrome, asthma, and …
hyperlipidemia, type 2 diabetes mellitus (T2DM), stroke, metabolic syndrome, asthma, and …