Glioblastoma remodelling of human neural circuits decreases survival

S Krishna, A Choudhury, MB Keough, K Seo, L Ni… - Nature, 2023 - nature.com
Gliomas synaptically integrate into neural circuits,. Previous research has demonstrated
bidirectional interactions between neurons and glioma cells, with neuronal activity driving …

Influences on cognitive outcomes in adult patients with gliomas: a systematic review

MA Kirkman, BHM Hunn, MSC Thomas… - Frontiers in …, 2022 - frontiersin.org
People with brain tumors, including those previously treated, are commonly affected by a
range of neurocognitive impairments involving executive function, memory, attention, and …

Cognitive impact of lower-grade gliomas and strategies for rehabilitation

C Weyer-Jamora, MS Brie, TL Luks… - Neuro-oncology …, 2021 - academic.oup.com
Outcomes for patients with lower-grade gliomas (LrGGs) continue to improve with advances
in molecular characterization and treatment. However, cognitive sequela from the tumor and …

Predicting survival in glioblastoma with multimodal neuroimaging and machine learning

PH Luckett, M Olufawo, B Lamichhane, KY Park… - Journal of Neuro …, 2023 - Springer
Purpose Glioblastoma (GBM) is the most common and aggressive malignant glioma, with an
overall median survival of less than two years. The ability to predict survival before treatment …

Widespread cortical functional disconnection in gliomas: an individual network mapping approach

E Silvestri, M Moretto, S Facchini… - Brain …, 2022 - academic.oup.com
Assessment of impaired/preserved cortical regions in brain tumours is typically performed
via intraoperative direct brain stimulation of eloquent areas or task-based functional MRI …

Functional and structural reorganization in brain tumors: a machine learning approach using desynchronized functional oscillations

J Falcó-Roget, A Cacciola, F Sambataro… - Communications …, 2024 - nature.com
Neuroimaging studies have allowed for non-invasive mapping of brain networks in brain
tumors. Although tumor core and edema are easily identifiable using standard MRI …

Personalized fMRI delineates functional regions preserved within brain tumors

W Cui, Y Wang, J Ren, CS Hubbard, X Fu… - Annals of …, 2022 - Wiley Online Library
Objective Accumulating evidence from invasive cortical stimulation mapping and
noninvasive neuroimaging studies indicates that brain function may be preserved within …

Structural connectome quantifies tumour invasion and predicts survival in glioblastoma patients

Y Wei, C Li, Z Cui, RC Mayrand, J Zou, ALKC Wong… - Brain, 2023 - academic.oup.com
Glioblastoma is characterized by diffuse infiltration into the surrounding tissue along white
matter tracts. Identifying the invisible tumour invasion beyond focal lesion promises more …

Neural signaling in cancer

MB Keough, M Monje - Annual review of neuroscience, 2022 - annualreviews.org
Nervous system activity regulates development, homeostasis, and plasticity of the brain as
well as other organs in the body. These mechanisms are subverted in cancer to propel …

The intervention, the patient and the illness–personalizing non-invasive brain stimulation in psychiatry

F Padberg, L Bulubas, Y Mizutani-Tiebel… - Experimental …, 2021 - Elsevier
Current hypotheses on the therapeutic action of non-invasive brain stimulation (NIBS) in
psychiatric disorders build on the abundant data from neuroimaging studies. This makes …