Background: Previous research has found relationships between specific indoor
environmental exposures and exacerbation of asthma. Objectives: In this review we provide …

Exposures to bioaerosols in the occupational environment are associated with a wide range
of health effects with major public health impact, including infectious diseases, acute toxic …

Aeroallergy results from maladaptive immune responses to ubiquitous, otherwise innocuous
environmental proteins. Although the proteins targeted by aeroallergic responses represent …

Members of the Toll-like receptor (TLR) family are key regulators of both innate and adaptive
immune responses. The function of TLRs in various human diseases has been investigated …

Toll-like receptors (TLRs) play an important part in the innate immune recognition of
invading microorganisms, initiating sufficient immune responses. Growing amounts of data …

Background Several recent studies have shown that growing up on a farm confers
significant protection against the development of atopy. These findings point particularly …

Despite the large amount of money spent on research into pollution of the indoor
environment, the problem remains complex with major gaps in our knowledge of the …

Background Chronic bronchitis in cigarette smokers shares many clinical and histologic
features with environmental lung diseases attributed to bacterial endotoxin …

▪ Abstract Asthma is a chronic disorder of the airways that is characterized by reversible
airflow obstruction and airway inflammation, persistent airway hyperreactivity, and airway …

Animal models have been developed to investigate specific components of asthmatic airway
inflammation, hyper‐responsiveness or remodelling. However, all of these aspects are …