The role of macrophages in the tumor microenvironment and tumor metabolism

P Sadhukhan, TY Seiwert - Seminars in Immunopathology, 2023 - Springer
The complexity and plasticity of the tumor microenvironment (TME) make it difficult to fully
understand the intratumoral regulation of different cell types and their activities …

Maximizing the value of indole-3-carbinol, from its distribution in dietary sources, health effects, metabolism, extraction, and analysis in food and biofluids

M Nagia, I Morgan, MA Gamel… - Critical Reviews in Food …, 2023 - Taylor & Francis
Abstract Indole-3-carbinol (I3C) is a major dietary component produced in Brassica
vegetables from glucosinolates (GLS) upon herbivores' attack. The compound is gaining …

Development of a self-nanoemulsifying drug delivery system of diindolylmethane for enhanced bioaccessibility, bioavailability and anti-breast cancer efficacy

J Natesh, Y Mukhlis, S Ramasamy, P Mondal… - Journal of Drug Delivery …, 2024 - Elsevier
Diindolylmethane (DIM), a bioactive compound rich in cruciferous vegetables, has been well
known for its health benefits, including anticancer properties. However, its clinical utilization …

Protective effect of diindolylmethane‐enriched dietary cabbage against doxorubicin‐induced cardiotoxicity in mice

J Natesh, P Mondal, D Penta, Y Mukhlis… - Journal of Applied …, 2024 - Wiley Online Library
Chemotherapy with doxorubicin (Dox) can lead to cardiotoxic effects, presenting a major
complication in cancer therapy. Diindolylmethane (DIM), derived from cruciferous …