Metabolic/inflammatory/vascular comorbidity in psychiatric disorders; soluble epoxide hydrolase (sEH) as a possible new target

W Swardfager, M Hennebelle, D Yu… - Neuroscience & …, 2018 - Elsevier
The common and severe psychiatric disorders, including major depressive disorder (MDD)
and bipolar disorder (BD), are associated with inflammation, oxidative stress and changes in …

An immunological age index in bipolar disorder: A confirmatory factor analysis of putative immunosenescence markers and associations with clinical characteristics

LB Rizzo, W Swardfager, PK Maurya… - … Journal of Methods …, 2018 - Wiley Online Library
Objectives The study aims to generate an immunological age (IA) trait on the basis of
immune cell differentiation parameters, and to test whether the IA is related to age and …

[HTML][HTML] Impact of mood on endothelial function and arterial stiffness in bipolar disorder

SL Schmitz, OJ Abosi, JE Persons, CA Sinkey… - Heart and …, 2018 - journals.lww.com
Background: Previous research on bipolar disorder demonstrates greater-than-expected
vascular dysfunction later in the course of illness, proportionate to the cumulative burden of …

[HTML][HTML] Obesogenic medications and weight gain over 24 weeks in patients with depression: results from the GUIDED study

JG Fiedorowicz, L Brown, J Li, SV Parikh… - Psychopharmacology …, 2021 - ncbi.nlm.nih.gov
Weight gain is a common side-effect of medications used to treat major depressive disorder
(MDD). We sought to estimate the frequency of weight gain for obesogenic medications …

Visceral adipose tissue in patients with severe mental illness

KG Kahl, M Deuschle, B Stubbs… - … Molecular Biology and …, 2018 - degruyter.com
Abstract Background Severe mental illnesses (SMIs), ie major depression, schizophrenia
and bipolar disorder, are associated with an elevated risk for the development of type-2 …