There are important sex differences in the brain that seem to arise from biology as well as
psychosocial influences. Sex differences in several aspects of human behavior and …

Growing empirical evidence suggests that nutrition and bacterial metabolites might impact
the systemic immune response in the context of disease and autoimmunity. We report that …

Experimental autoimmune encephalomyelitis is a model for multiple sclerosis. Here we
show that induction generates successive waves of clonally expanded CD4+, CD8+ and γδ+ …

Experimental autoimmune encephalomyelitis (EAE) can be induced in many animal strains
by inoculation with central nervous system antigens and adjuvant or by the passive transfer …

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system. The
etiology of MS is multifactorial, with disease risk determined by genetics and environmental …

Multiple sclerosis (MS) is an immune-mediated disease that targets the myelin sheath of
central nervous system (CNS) neurons leading to axon injury, neuronal death, and …

Spinal cord injury (SCI) is a destructive polyneuropathy that can result in loss of
sensorimotor function and sphincter dysfunction, and even death in critical situations …

High-fat diets (HFD) are linked to obesity and associated comorbidities and induce
pathogenic T helper (Th) 17 cells while decreasing regulatory T cells (Treg). This pro …

Neuroinflammation leads to tissue injury causing many of the clinical symptoms of Multiple
Sclerosis, an autoimmune disorder of the central nervous system (CNS). While T cells …

Multiple sclerosis (MS) is a debilitating autoimmune neuroinflammatory disease influenced
by genetics and the environment. MS incidence in female subjects has approximately tripled …