[PDF][PDF] Control engineering methods for blood glucose levels regulation

J Tašić, M Takács, L Kovács - Acta Polytechnica Hungarica, 2022 - researchgate.net
In this article, we review recently proposed, advanced methods, for the control of blood
glucose levels, in patients with type 1 diabetes. The proposed methods are based on …

[HTML][HTML] A regularized Moving Horizon Estimator for combined state and parameter estimation in a bioprocess experimental application

A Tuveri, CSM Nakama, J Matias, HE Holck… - Computers & Chemical …, 2023 - Elsevier
Due to the lack or high costs of measurement devices to monitor and control metabolites in
microbial cultivation processes, state estimators are often required. These estimators …

Nonlinear model predictive control and artificial pancreas technologies

D Boiroux, JB Jørgensen - 2018 ieee conference on decision …, 2018 - ieeexplore.ieee.org
A single-hormone artificial pancreas (AP) for people with type 1 diabetes consists of a
continuous glucose monitor (CGM), a control algorithm, and an insulin pump for …

A new stochastic approach for modeling glycemic disturbances in type 2 diabetes

HG Clausen, T Knudsen, M Al Ahdab… - IEEE Transactions …, 2021 - ieeexplore.ieee.org
Objective: To improve insulin treatment in type 2 diabetes (T2D) using model-based control
techniques, the underlying model needs to be individualized to each patient. Due to the …

A nonlinear model predictive control strategy for glucose control in people with type 1 diabetes

D Boiroux, JB Jørgensen - IFAC-PapersOnLine, 2018 - Elsevier
In this paper, we evaluate the closed-loop performance of a control algorithm for the
treatment of type 1 diabetes (T1D) identified from prior continuous glucose monitor (CGM) …

Efficient computation of the continuous-discrete extended Kalman filter sensitivities applied to maximum likelihood estimation

D Boiroux, TKS Ritschel, NK Poulsen… - 2019 IEEE 58th …, 2019 - ieeexplore.ieee.org
In this paper, we present and compare different methods for computing the likelihood
function and its gradient. We consider nonlinear continuous-discrete models described by a …

Parameter estimation for a jump diffusion model of type 2 diabetic patients in the presence of unannounced meals

M Al Ahdab, M Papež, T Knudsen… - … IEEE Conference on …, 2021 - ieeexplore.ieee.org
Type 2 diabetes (T2D) has become one of the most often encountered metabolic disorders
threatening the human health. Unannounced meal intake and irregular physical activity …

State estimation in type 2 diabetes using the continuous-discrete unscented Kalman filter

HG Clausen, J Leth, T Knudsen, H Schiøler - IFAC-PapersOnLine, 2020 - Elsevier
Using a nonlinear model for the glucose-insulin dynamics in type 2 diabetes, formulated in
continuous-time as a stochastic differential equation, we seek to estimate the system states …

Correlation in Dose-Response to Rapid-and Long-Acting Insulin for People with Type 1 Diabetes

SE Engell, TB Aradóttir, H Bengtsson… - 2022 44th Annual …, 2022 - ieeexplore.ieee.org
In diabetes, it can become necessary to switch between pump-and pen-based insulin
treatment. This switch involves a translation between rapid-and long-acting insulin …

Stochastic Modeling and Inference for Type 2 Diabetes

M Al Ahdab, M Papež, T Knudsen, TB Aradóttir… - Authorea …, 2023 - techrxiv.org
Type 2 diabetes (T2D) is a common metabolic disorder that poses threat to human health.
Blood glucose (BG) concentrations in T2D subjects can be influenced by various factors …