The pharmacoresistant epilepsy: an overview on existant and new emerging therapies

A Fattorusso, S Matricardi, E Mencaroni… - Frontiers in …, 2021 - frontiersin.org
Epilepsy is one of the most common neurological chronic disorders, with an estimated
prevalence of 0. 5–1%. Currently, treatment options for epilepsy are predominantly based on …

Underutilization of epilepsy surgery: Part I: A scoping review of barriers

D Samanta, AP Ostendorf, E Willis, R Singh… - Epilepsy & Behavior, 2021 - Elsevier
One-third of persons with epilepsy have seizures despite appropriate medical therapy. Drug
resistant epilepsy (DRE) is associated with neurocognitive and psychological decline, poor …

Pediatric epilepsy surgery from 2000 to 2018: Changes in referral and surgical volumes, patient characteristics, genetic testing, and postsurgical outcomes

MH Eriksson, KJ Whitaker, J Booth, RJ Piper… - …, 2023 - Wiley Online Library
Objective Neurosurgery is a safe and effective form of treatment for select children with drug‐
resistant epilepsy. Still, there is concern that it remains underutilized, and that seizure …

A neuromorphic spiking neural network detects epileptic high frequency oscillations in the scalp EEG

K Burelo, G Ramantani, G Indiveri, J Sarnthein - Scientific Reports, 2022 - nature.com
Abstract Interictal High Frequency Oscillations (HFO) are measurable in scalp EEG. This
development has aroused interest in investigating their potential as biomarkers of …

Intracranial neuromodulation with deep brain stimulation and responsive neurostimulation in children with drug-resistant epilepsy: a systematic review

M Khan, J Paktiawal, RJ Piper, A Chari… - Journal of Neurosurgery …, 2021 - thejns.org
OBJECTIVE In children with drug-resistant epilepsy (DRE), resective, ablative, and
disconnective surgery may not be feasible or may fail. Neuromodulation in the form of deep …

Underutilization of epilepsy surgery: Part II: Strategies to overcome barriers

D Samanta, R Singh, S Gedela, MS Perry, R Arya - Epilepsy & Behavior, 2021 - Elsevier
Interventions focused on utilization of epilepsy surgery can be divided into groups: those that
improve patients' access to surgical evaluation and those that facilitate completion of the …

The surgical treatment of epilepsy

A Consales, S Casciato, S Asioli, C Barba, M Caulo… - Neurological …, 2021 - Springer
Abstract In 2009, the Commission for Epilepsy Surgery of the Italian League Against
Epilepsy (LICE) conducted an overview about the techniques used for the pre-surgical …

Microelectrode recordings in human epilepsy: a case for clinical translation

A Chari, RC Thornton, MM Tisdall… - Brain …, 2020 - academic.oup.com
With their 'all-or-none'action potential responses, single neurons (or units) are accepted as
the basic computational unit of the brain. There is extensive animal literature to support the …

Seizure outcome determinants in children after surgery for single unilateral lesions on magnetic resonance imaging: Role of preoperative ictal and interictal …

F Castro‐Villablanca, F Moeller, S Pujar, F D'Arco… - …, 2022 - Wiley Online Library
Objective To determine whether an ictal electroencephalographic (EEG) recording as part of
presurgical evaluation of children with a demarcated single unilateral magnetic resonance …

The latest advances in the pharmacological management of focal epilepsies in children: a narrative review

S Matricardi, G Scorrano, G Prezioso… - Expert Review of …, 2024 - Taylor & Francis
Introduction Focal epilepsy constitutes the most common epilepsy in children, and medical
treatment represents the first-line therapy in this condition. The main goal of medical …