Influence of intersignaling crosstalk on the intracellular localization of YAP/TAZ in lung cells
IA Govorova, SY Nikitochkina, EA Vorotelyak - Cell Communication and …, 2024 - Springer
A cell is a dynamic system in which various processes occur simultaneously. In particular,
intra-and intercellular signaling pathway crosstalk has a significant impact on a cell's life …
intra-and intercellular signaling pathway crosstalk has a significant impact on a cell's life …
The Reign of Follistatin in Tumors and Their Microenvironment: Implications for Drug Resistance
J Sosa, A Oyelakin, S Sinha - Biology, 2024 - mdpi.com
Simple Summary Within the extracellular milieu surrounding cancer cells exists an
ecosystem of heterogeneous cell populations that dictate tumor growth and survival via cell …
ecosystem of heterogeneous cell populations that dictate tumor growth and survival via cell …
Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
K Graham, P Lienau, B Bader, S Prechtl, J Naujoks… - Cell Chemical …, 2024 - cell.com
This study describes the identification and target deconvolution of small molecule inhibitors
of oncogenic Yes-associated protein (YAP1)/TAZ activity with potent anti-tumor activity in …
of oncogenic Yes-associated protein (YAP1)/TAZ activity with potent anti-tumor activity in …
[HTML][HTML] Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity
L Peng, L Zhou, H Li, X Zhang, S Li, K Wang, M Yang… - Cell Reports, 2024 - cell.com
The major histocompatibility complex class I (MHC class I)-mediated tumor antigen
processing and presentation (APP) pathway is essential for the recruitment and activation of …
processing and presentation (APP) pathway is essential for the recruitment and activation of …
[HTML][HTML] SIRPG promotes lung squamous cell carcinoma pathogenesis via M1 macrophages: a multi-omics study integrating data and Mendelian randomization
G Mao, J Li, N Wang, H Yu, S Han, M Xiang… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Background Squamous cell carcinoma of the lung (LUSC) is a severe and highly lethal
malignant tumor of the respiratory system, and its molecular mechanisms at the molecular …
malignant tumor of the respiratory system, and its molecular mechanisms at the molecular …
Graph perceiver network for lung tumor and bronchial premalignant lesion stratification from histopathology
Bronchial premalignant lesions (PMLs) precede the development of invasive lung
squamous cell carcinoma (LUSC), posing a significant challenge in distinguishing those …
squamous cell carcinoma (LUSC), posing a significant challenge in distinguishing those …
Premalignant Progression in the Lung: Knowledge Gaps and Novel Opportunities for Interception of Non–Small Cell Lung Cancer. An Official American Thoracic …
Rationale: Despite significant advances in precision treatments and immunotherapy, lung
cancer is the most common cause of cancer death worldwide. To reduce incidence and …
cancer is the most common cause of cancer death worldwide. To reduce incidence and …
Analysis of Methylome of Different Forms of Basal Cell Hyperplasia and Squamous Cell Metaplasia of Bronchial Epithelium
AA Ponomaroyva, AA Schegoleva, PA Gervas… - Bulletin of Experimental …, 2024 - Springer
Squamous cell lung cancer (SCLC) occurs as a result of dysregenerative changes in the
bronchial epithelium: basal cell hyperplasia (BCH), squamous cell metaplasia (SM), and …
bronchial epithelium: basal cell hyperplasia (BCH), squamous cell metaplasia (SM), and …