Identified 50 years ago, mesenchymal stromal/stem cells (MSCs) immediately generated a
substantial interest among the scientific community because of their differentiation plasticity …

The survival of engineered tissue constructs during the initial phase after their implantation
depends on the rapid development of an adequate vascularization. This, in turn, is a major …

There is a clear clinical need for cell therapies to repair or regenerate tissue lost to disease
or trauma. Adipose tissue is a renewable source of stem cells, called adipose-derived stem …

In the past few years, interest in adipose tissue as an ideal source of mesenchymal stem
cells (MSCs) has increased. These cells are multipotent and may differentiate in vitro into …

Purpose Osteoarthritis (OA) represents a relevant social and economic burden worldwide.“
Mesenchymal stem cells” or, as recently proposed,“medicinal signaling cells”(MSCs) have …

Adult mesenchymal stem cells (MSCs) have profound medicinal effects at body sites of
tissue injury, disease, or inflammation as either endogenously or exogenously supplied. The …

Neurodegenerative diseases resulting from the progressive loss of structure and/or function
of neurons contribute to different paralysis degrees and loss of cognition and sensation. The …

Current cell-based repair strategies have proven unsuccessful for treating cartilage defects
and osteoarthritic lesions, consequently advances in innovative therapeutics are required …

In the past decade, adipose tissue became a highly interesting source of adult stem cells for
plastic surgery and regenerative medicine. The isolated stromal vascular fraction (SVF) is a …

With the insufficient satisfaction rates and high cost of operative treatment for osteoarthritis
(OA), alternatives have been sought. Furthermore, the inability of current medications to …