Spinal cord injury: molecular mechanisms and therapeutic interventions
X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …
The challenges of SCI repair include its complex pathological mechanisms and the …
Multifaceted role of phyto-derived polyphenols in nanodrug delivery systems
As naturally occurring bioactive products, several lines of evidence have shown the potential
of polyphenols in the medical intervention of various diseases, including tumors …
of polyphenols in the medical intervention of various diseases, including tumors …
High drug-loaded microspheres enabled by controlled in-droplet precipitation promote functional recovery after spinal cord injury
W Li, J Chen, S Zhao, T Huang, H Ying… - Nature …, 2022 - nature.com
Drug delivery systems with high content of drug can minimize excipients administration,
reduce side effects, improve therapeutic efficacy and/or promote patient compliance …
reduce side effects, improve therapeutic efficacy and/or promote patient compliance …
pH switchable nanoplatform for in vivo persistent luminescence imaging and precise photothermal therapy of bacterial infection
LX Yan, LJ Chen, X Zhao… - Advanced Functional …, 2020 - Wiley Online Library
Photothermal therapy (PTT) is one of the most promising approaches to combat multidrug‐
resistant bacteria with less potential to induce resistance and systemic toxicity. However …
resistant bacteria with less potential to induce resistance and systemic toxicity. However …
Preparation, characterization and antioxidant activity of protocatechuic acid grafted carboxymethyl chitosan and its hydrogel
In this study, protocatechuic acid (PCA) was grafted onto carboxymethyl chitosan (CMCS)
via EDC/NHS to improve the antioxidant effect. The grafting ratio of PCA-g-CMCS …
via EDC/NHS to improve the antioxidant effect. The grafting ratio of PCA-g-CMCS …
Regenerative therapies for spinal cord injury
Spinal cord injury (SCI) is a serious problem that primarily affects younger and middle-aged
adults at its onset. To date, no effective regenerative treatment has been developed. Over …
adults at its onset. To date, no effective regenerative treatment has been developed. Over …
Ferulic acid: a hope for Alzheimer's disease therapy from plants
A Sgarbossa, D Giacomazza, M Di Carlo - Nutrients, 2015 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the deposition of
extracellular amyloid-beta peptide (Aβ) and intracellular neurofibrillar tangles, associated …
extracellular amyloid-beta peptide (Aβ) and intracellular neurofibrillar tangles, associated …
Polyphenol-chitosan conjugates: Synthesis, characterization, and applications
Chitosan, the only positively charged polysaccharide in the world, is very attractive for food,
medicinal and pharmaceutical applications because of its promising properties, including …
medicinal and pharmaceutical applications because of its promising properties, including …
Applications of chitosan-based biomaterials: From preparation to spinal cord injury neuroprosthetic treatment
W Xiang, H Cao, H Tao, L Jin, Y Luo, F Tao… - International Journal of …, 2023 - Elsevier
Spinal cord injury (SCI)-related disabilities are a serious problem in the modern society.
Further, the treatment of SCI is highly challenging and is urgently required in clinical …
Further, the treatment of SCI is highly challenging and is urgently required in clinical …
Role of phenolic compounds in human disease: current knowledge and future prospects
Inflammation is a natural protective mechanism that occurs when the body's tissue
homeostatic mechanisms are disrupted by biotic, physical, or chemical agents. The immune …
homeostatic mechanisms are disrupted by biotic, physical, or chemical agents. The immune …