Pyrazolone structural motif in medicinal chemistry: Retrospect and prospect

Z Zhao, X Dai, C Li, X Wang, J Tian, Y Feng… - European journal of …, 2020 - Elsevier
The pyrazolone structural motif is a critical element of drugs aimed at different biological end-
points. Medicinal chemistry researches have synthesized drug-like pyrazolone candidates …

Recent advances in acylpyrazolone metal complexes and their potential applications

F Marchetti, R Pettinari, C Pettinari - Coordination Chemistry Reviews, 2015 - Elsevier
This review is aimed at updating the current advance of metal complexes bearing
acylpyrazolonate ligands. Novel synthetic procedures for acylpyrazolones are reported …

Syntheses and Characterization of Main Group, Transition Metal, Lanthanide, and Actinide Complexes of Bidentate Acylpyrazolone Ligands

T Mies, AJP White, HS Rzepa, L Barluzzi… - Inorganic …, 2023 - ACS Publications
The synthesis of acylpyrazolone salts and their complexes of main group elements,
transition metals, lanthanides, and actinides are described and characterized inter alia by …

Crystal feature and spectral characterization of Zn (II) complexes containing Schiff base of Acylpyrazolone ligand with antimalarial action

I Shaikh, M Travadi, RN Jadeja, RJ Butcher… - Journal of the Indian …, 2022 - Elsevier
With association of acylpyrazolones and benzhydrazide, two novel Ligands BZ-PCBMCPMP
((Z)-N'-((4-chlorophenyl)(1-(3-chlorophenyl) 3-methyl-5-oxo-1, 5-dihydro-4H-pyrazol-4 …

A mononuclear copper (II) complex based on the polypyridyl ligand 2, 4, 6-tris (2-pyridyl)-1, 3, 5-triazine (tptz),[Cu (tptz) 2] 2+: X-ray crystal structure, DNA binding and …

K Abdi, H Hadadzadeh, M Salimi, J Simpson… - Polyhedron, 2012 - Elsevier
A water soluble 1, 3, 5-triazine-based copper (II) complex,[Cu (tptz) 2] 2+, where tptz is 2, 4,
6-tris (2-pyridyl)-1, 3, 5-triazine, has been prepared and characterized by elemental analysis …

A new pyrazolone based ternary Cu (II) complex: Synthesis, characterization, crystal structure, DNA binding, protein binding and anti-cancer activity towards A549 …

KM Vyas, RN Jadeja, D Patel, RV Devkar, VK Gupta - Polyhedron, 2013 - Elsevier
With the aim of exploring the anticancer properties of coordination compounds, we report for
the first time the synthesis of the new ternary complex [Cu (TMCPMP-TS)(Phen)](TMCPMP …

Three mixed ligand mononuclear Zn (II) complexes of 4-acyl pyrazolones: synthesis, characterization, crystal study and anti-malarial activity

I Shaikh, RN Jadeja, R Patel - Polyhedron, 2020 - Elsevier
Three novel mixed ligand Zn (II) complexes {complex 1=[Zn (L1) 2 (bpy)], complex 2=[Zn
(L2) 2 (bpy)], complex 3=[Zn (L2) 2 (phen)], where bpy= 2, 2′-bipyridine and phen= 1, 10 …

4-Acylhydrazone-5-pyrazolones and their zinc (II) metal complexes: synthesis, characterization, crystal feature and antimalarial activity

I Shaikh, RN Jadeja, R Patel, V Mevada… - Journal of Molecular …, 2021 - Elsevier
Abstract Two novel 4-acylhydrazone-5-pyrazolones (L 1=(Z)-N'-((4-chlorophenyl)(3-methyl-5-
oxo-1-(p-tolyl)-4, 5-dihydro-1H-pyrazol-4-yl) methylene) benzohydrazide and L 2=(Z)-N'-((4 …

Zinc(II) Complex with Pyrazolone-Based Hydrazones is Strongly Effective against Trypanosoma brucei Which Causes African Sleeping Sickness

F Marchetti, A Tombesi, C Di Nicola… - Inorganic …, 2022 - ACS Publications
Two pyrazolone-based hydrazones H2L′[in general, H2L′; in detail, H 2 L 1= 5-methyl-2-
phenyl-4-(2-phenyl-1-(2-(4-(trifluoromethyl) phenyl) hydrazineyl) ethyl)-2, 4-dihydro-3 H …

Copper (II) Complexes of 5–Fluoro–Salicylaldehyde: Synthesis, Characterization, Antioxidant Properties, Interaction with DNA and Serum Albumins

Z Papadopoulos, E Doulopoulou, A Zianna… - Molecules, 2022 - mdpi.com
The synthesis, characterization and biological profile (antioxidant capacity, interaction with
calf-thymus DNA and serum albumins) of five neutral copper (II) complexes of 5–fluoro …