Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new players
X Yuan, C Larsson, D Xu - Oncogene, 2019 - nature.com
Long-lived species Homo sapiens have evolved robust protection mechanisms against
cancer by repressing telomerase and maintaining short telomeres, thereby delaying the …
cancer by repressing telomerase and maintaining short telomeres, thereby delaying the …
Current management of pheochromocytoma/paraganglioma: a guide for the practicing clinician in the era of precision medicine
S Nölting, M Ullrich, J Pietzsch, CG Ziegler… - Cancers, 2019 - mdpi.com
Pheochromocytomas and paragangliomas (PCC/PGLs) are rare, mostly catecholamine-
producing neuroendocrine tumors of the adrenal gland (PCCs) or the extra-adrenal …
producing neuroendocrine tumors of the adrenal gland (PCCs) or the extra-adrenal …
The North American Neuroendocrine Tumor Society consensus guidelines for surveillance and management of metastatic and/or unresectable pheochromocytoma …
L Fishbein, J Del Rivero, T Else, JR Howe, SL Asa… - Pancreas, 2021 - journals.lww.com
This manuscript is the result of the North American Neuroendocrine Tumor Society
consensus conference on the medical management and surveillance of metastatic and …
consensus conference on the medical management and surveillance of metastatic and …
Metastatic pheochromocytomas and abdominal paragangliomas
D Granberg, CC Juhlin… - The journal of clinical …, 2021 - academic.oup.com
Abstract Context Pheochromocytomas and paragangliomas (PPGLs) are believed to harbor
malignant potential; about 10% to 15% of pheochromocytomas and up to 50% of abdominal …
malignant potential; about 10% to 15% of pheochromocytomas and up to 50% of abdominal …
Genetic bases of pheochromocytoma and paraganglioma
The genetics of pheochromocytoma and paraganglioma (PPGL) has become increasingly
complex over the last two decades. The list of genes involved in the development of these …
complex over the last two decades. The list of genes involved in the development of these …
Super-enhancer function and its application in cancer targeted therapy
F Tang, Z Yang, Y Tan, Y Li - NPJ precision oncology, 2020 - nature.com
Abstract Recently, super-enhancers (SEs) have been identified as a unique type of
transcriptional regulation involved in cancer development. SEs exhibit a size, high …
transcriptional regulation involved in cancer development. SEs exhibit a size, high …
Genotype–phenotype correlations in pheochromocytoma and paraganglioma: a systematic review and individual patient meta-analysis
Pheochromocytoma and paraganglioma (PPGL) can be divided into at least four molecular
subgroups. Whether such categorizations are independent factors for prognosis or …
subgroups. Whether such categorizations are independent factors for prognosis or …
Challenges in paragangliomas and pheochromocytomas: from histology to molecular immunohistochemistry
CC Juhlin - Endocrine pathology, 2021 - Springer
Abdominal paragangliomas and pheochromocytomas (PPGLs) are rare neuroendocrine
tumors of the infradiaphragmatic paraganglia and adrenal medulla, respectively. Although …
tumors of the infradiaphragmatic paraganglia and adrenal medulla, respectively. Although …
Pheochromocytomas and abdominal paragangliomas: a practical guidance
Simple Summary Pheochromocytomas and abdominal paragangliomas (PPGLs) are rare.
They can be discovered incidentally by imaging with computed tomography or magnetic …
They can be discovered incidentally by imaging with computed tomography or magnetic …
[HTML][HTML] Determinants of disease-specific survival in patients with and without metastatic pheochromocytoma and paraganglioma
C Pamporaki, T Prodanov, L Meuter… - European Journal of …, 2022 - Elsevier
Abstract Background Pheochromocytomas and paragangliomas (PPGLs) have a
heterogeneous prognosis, the basis of which remains unclear. We, therefore, assessed …
heterogeneous prognosis, the basis of which remains unclear. We, therefore, assessed …